| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4141669 | B | Binding affinity to poly(dA-dT)n DNA (unknown origin) assessed as change in melting temperature at 0.3 molar ratio of compound:DNA by spectrophotometric analysis | Not specified | 7 | nucleic acid format | Scientific Literature | ||
| 2. | ALA4141670 | F | Antiprotozoal activity against bloodstream form of Trypanosoma brucei rhodesiense STIB900 after 70 hrs by resazurin solution-based assay | Trypanosoma brucei rhodesiense | 7 | organism-based format | Scientific Literature | ||
| 3. | ALA4141671 | F | Antimalarial activity against Plasmodium falciparum K1 infected in human erythrocytes assessed as reduction in [3H]hypoxanthine incorporation preincubated for 48 hrs followed by [3H]hypoxanthine addition measured after 24 hrs by liquid scintillation counting | Plasmodium falciparum | 7 | organism-based format | Scientific Literature | ||
| 4. | ALA4141672 | A | Cytotoxicity against rat L6 cells | Rattus norvegicus | 7 | cell-based format | Scientific Literature | ||
| 5. | ALA4141673 | T | Selectivity index, ratio of IC50 for rat L6 cells to IC50 for bloodstream form of Trypanosoma brucei rhodesiense STIB900 | 7 | assay format | Scientific Literature | |||
| 6. | ALA4141674 | T | Selectivity index, ratio of IC50 for rat L6 cells to IC50 for Plasmodium falciparum K1 infected in human erythrocytes | 7 | cell-based format | Scientific Literature | |||
| 7. | ALA4141675 | F | Antiprotozoal activity against bloodstream forms of Trypanosoma brucei rhodesiense STIB900 infected in NMR1 mouse at 5 mg/kg, ip administered daily for 4 consecutive days starting from day 3 to 6 post infection | Trypanosoma brucei rhodesiense | 7 | organism-based format | Scientific Literature |
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