| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4150900 | A | Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system and measured after 15 mins by UPLC-MS analysis | Homo sapiens | 37 | microsome format | Scientific Literature | ||
| 2. | ALA4150901 | A | Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system and measured after 15 mins by UPLC-MS analysis | Homo sapiens | 37 | microsome format | Scientific Literature | ||
| 3. | ALA4150902 | A | Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system and measured after 15 mins by UPLC-MS analysis | Homo sapiens | 37 | microsome format | Scientific Literature | ||
| 4. | ALA4150903 | A | Inhibition of CYP2C8 in human liver microsomes using amodiaquine as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system and measured after 15 mins by UPLC-MS analysis | Homo sapiens | 37 | microsome format | Scientific Literature | ||
| 5. | ALA4150904 | A | Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system and measured after 15 mins by UPLC-MS analysis | Homo sapiens | 37 | microsome format | Scientific Literature | ||
| 6. | ALA4150905 | A | Inhibition of CYP2C19 in human liver microsomes using omeprazole as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system and measured after 15 mins by UPLC-MS analysis | Homo sapiens | 37 | microsome format | Scientific Literature | ||
| 7. | ALA4150906 | A | Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system and measured after 15 mins by UPLC-MS analysis | Homo sapiens | 37 | microsome format | Scientific Literature | ||
| 8. | ALA4150907 | A | Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system and measured after 15 mins by UPLC-MS analysis | Homo sapiens | 37 | microsome format | Scientific Literature | ||
| 9. | ALA4150908 | A | Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system and measured after 15 mins by UPLC-MS analysis | Homo sapiens | 37 | microsome format | Scientific Literature | ||
| 10. | ALA4150909 | B | Selectivity index, ratio of IC50 for CYP3A4 in human liver microsomes to IC50 for CYP2A6 in human liver microsomes | Homo sapiens | 37 | assay format | Scientific Literature | ||
| 11. | ALA4150910 | B | Selectivity index, ratio of IC50 for CYP2D6 in human liver microsomes to IC50 for CYP2A6 in human liver microsomes | Homo sapiens | 37 | assay format | Scientific Literature | ||
| 12. | ALA4150911 | B | Selectivity index, ratio of IC50 for CYP2C9 in human liver microsomes to IC50 for CYP2A6 in human liver microsomes | Homo sapiens | 37 | assay format | Scientific Literature | ||
| 13. | ALA4150912 | B | Selectivity index, ratio of IC50 for CYP2C19 in human liver microsomes to IC50 for CYP2A6 in human liver microsomes | Homo sapiens | 37 | assay format | Scientific Literature | ||
| 14. | ALA4150913 | B | Selectivity index, ratio of IC50 for CYP1A2 in human liver microsomes to IC50 for CYP2A6 in human liver microsomes | Homo sapiens | 37 | assay format | Scientific Literature | ||
| 15. | ALA4150914 | B | Selectivity index, ratio of IC50 for CYP2B6 in human liver microsomes to IC50 for CYP2A6 in human liver microsomes | Homo sapiens | 37 | assay format | Scientific Literature | ||
| 16. | ALA4150915 | B | Selectivity index, ratio of IC50 for CYP2C8 in human liver microsomes to IC50 for CYP2A6 in human liver microsomes | Homo sapiens | 37 | assay format | Scientific Literature | ||
| 17. | ALA4150916 | B | Selectivity index, ratio of IC50 for CYP2E1 in human liver microsomes to IC50 for CYP2A6 in human liver microsomes | Homo sapiens | 37 | assay format | Scientific Literature | ||
| 18. | ALA4150917 | A | Half life in human liver microsomes at 10 uM up to 2 hrs at 37 degC in presence of NADPH-regenerating system by UPLC/MS analysis | Homo sapiens | 18 | microsome format | Scientific Literature |
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