| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4141503 | B | Inhibition of human recombinant full-length HDAC1 (1 to 482 residues) expressed in baculovirus using Boc-Lys(acetyl)-AMC as substrate after 30 mins by fluorescence assay | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 2. | ALA4141504 | B | Inhibition of human recombinant full-length HDAC6 expressed in baculovirus infected Sf9 cells using Boc-Lys(acetyl)-AMC as substrate after 30 mins by fluorescence assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 3. | ALA4141505 | B | Inhibition of human recombinant full-length C-terminal GST-tagged HDAC2 expressed in baculovirus infected Sf9 cells using Boc-Lys(acetyl)-AMC as substrate after 30 mins by fluorescence assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 4. | ALA4141506 | B | Inhibition of human recombinant full-length C-terminal GST-tagged HDAC3 expressed in baculovirus infected Sf9 cells using Boc-Lys(acetyl)-AMC as substrate after 30 mins by fluorescence assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 5. | ALA4141515 | B | Inhibition of HDAC1/2/3 in human A549 cells assessed as increase in acetylated acetylated histone H4 levels at 500 nM after 3 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA4141518 | B | Binding affinity to HDAC6 in aggresomes of human A549 cells assessed as formation of aggresome-like structures at 2 uM added after 24 hrs pre-treatment with MG132 followed by compound addition measured after 2 hrs by fluorescence staining-based confocal microscopic analysis | Homo sapiens | 3 | assay format | Scientific Literature |
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