# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4149596 | F | Neuroprotective activity against glutamate-induced apoptotic cell death in rat PC12 cells assessed as decrease in caspase-3 level at 10 to 40 uM measured after 24 hrs | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
2. | ALA4149597 | F | Neuroprotective activity against glutamate-induced neuronal cell death in rat PC12 cells assessed as increase in cell viability pretreated for 2 hrs followed by glutamate challenge measured after 24 hrs by MTT assay | Rattus norvegicus | 31 | cell-based format | Scientific Literature | ||
3. | ALA4149598 | F | Neuroprotective activity against glutamate-induced apoptotic cell death in rat PC12 cells assessed as apoptotic neurons at 10 to 40 uM pretreated with compound followed by glutamate challenge measured after 24 hrs by Hoechst 33258 staining based assay (Rvb = 65.5%) | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
4. | ALA4149599 | B | Increase in Akt phosphorylation in glutamate-induced rat PC12 cells at 10 to 40 uM measured after 24 hrs by Western blot analysis | Rattus norvegicus | 1 | assay format | Scientific Literature |