# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4136392 | Functional | Antiviral activity against wild type HIV1 3B infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect after 5 days by MTT assay | Human immunodeficiency virus 1 | 12 | ALA4130567 | organism-based format | Scientific Literature | |
2. | ALA4136393 | Functional | Antiviral activity against HIV2 ROD infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect after 5 days by MTT assay | Human immunodeficiency virus 2 | 11 | ALA4130567 | organism-based format | Scientific Literature | |
3. | ALA4136394 | ADME | Cytotoxicity against human MT4 cells assessed as reduction in cell viability after 5 days by MTT assay | Homo sapiens | 12 | ALA4130567 | cell-based format | Scientific Literature | |
4. | ALA4136395 | Toxicity | Selectivity index, ratio of CC50 for human MT4 cells to EC50 for wild type HIV1 3B infected in human MT4 cells | 12 | ALA4130567 | cell-based format | Scientific Literature | ||
5. | ALA4136396 | Functional | Antiviral activity against HIV1 3B harboring reverse transcriptase L100I mutant infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect after 5 days by MTT assay | Human immunodeficiency virus 1 | 12 | ALA4130567 | organism-based format | Scientific Literature | |
6. | ALA4136397 | Functional | Antiviral activity against HIV1 3B harboring reverse transcriptase K103N mutant infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect after 5 days by MTT assay | Human immunodeficiency virus 1 | 12 | ALA4130567 | organism-based format | Scientific Literature | |
7. | ALA4136398 | Functional | Antiviral activity against HIV1 3B harboring reverse transcriptase Y181C mutant infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect after 5 days by MTT assay | Human immunodeficiency virus 1 | 12 | ALA4130567 | organism-based format | Scientific Literature | |
8. | ALA4136399 | Functional | Antiviral activity against HIV1 3B harboring reverse transcriptase Y188L mutant infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect after 5 days by MTT assay | Human immunodeficiency virus 1 | 12 | ALA4130567 | organism-based format | Scientific Literature | |
9. | ALA4136400 | Functional | Antiviral activity against HIV1 3B harboring reverse transcriptase E138K mutant infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect after 5 days by MTT assay | Human immunodeficiency virus 1 | 12 | ALA4130567 | organism-based format | Scientific Literature | |
10. | ALA4136401 | Functional | Antiviral activity against HIV1 3B harboring reverse transcriptase F227L/V106A double mutant infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect after 5 days by MTT assay | Human immunodeficiency virus 1 | 12 | ALA4130567 | organism-based format | Scientific Literature | |
11. | ALA4136402 | Functional | Antiviral activity against HIV1 3B harboring reverse transcriptase RES056 double mutant infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect after 5 days by MTT assay | Human immunodeficiency virus 1 | 12 | ALA4130567 | organism-based format | Scientific Literature |