# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4154411 | B | Inhibition of human TRPM2 expressed in HEK293 cells assessed as reduction in ADPR-induced channel currents at 30 uM treated extracellularly after 60 secs by whole cell patch clamp electrophysiology method relative to control | Homo sapiens | 27 | ALA4152243 | cell-based format | Scientific Literature | |
2. | ALA4154412 | B | Inhibition of human TRPM2 expressed in HEK293 cells assessed as reduction in ADPR-induced channel currents treated extracellularly after 60 secs by whole cell patch clamp electrophysiology method | Homo sapiens | 26 | ALA4152243 | cell-based format | Scientific Literature | |
3. | ALA4154413 | B | Inhibition of human TRPM2 H995A mutant expressed in HEK293 cells assessed as reduction in ADPR-induced channel currents at 30 uM treated extracellularly after 50 to 200 secs by whole cell patch clamp electrophysiology method | Homo sapiens | 3 | ALA4152243 | cell-based format | Scientific Literature | |
4. | ALA4154414 | B | Inhibition of human TRPM2 D964A mutant expressed in HEK293 cells assessed as reduction in ADPR-induced channel currents at 30 uM treated extracellularly after 50 to 200 secs by whole cell patch clamp electrophysiology method relative to control | Homo sapiens | 3 | ALA4152243 | cell-based format | Scientific Literature | |
5. | ALA4154415 | B | Inhibition of human TRPM2 expressed in HEK293 cells assessed as reduction in ADPR-induced channel currents at 3 uM treated extracellularly after 60 secs by whole cell patch clamp electrophysiology method relative to control | Homo sapiens | 25 | ALA4152243 | cell-based format | Scientific Literature | |
6. | ALA4154416 | B | Inhibition of human TRPM8 expressed in HEK293 cells assessed as reduction in menthol-induced channel currents at 30 uM treated extracellularly after 60 secs by whole cell patch clamp electrophysiology method relative to control | Homo sapiens | 4 | ALA4152243 | cell-based format | Scientific Literature | |
7. | ALA4154417 | B | Inhibition of human TRPM8 expressed in HEK293 cells assessed as reduction in menthol-induced channel currents at 30 uM treated intracellularly via pipette after 60 secs by whole cell patch clamp electrophysiology method | Homo sapiens | 4 | ALA4152243 | cell-based format | Scientific Literature | |
8. | ALA4835353 | B | Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiology | Homo sapiens | 16 | ALA4834416 | cell-based format | Scientific Literature | |
9. | ALA4835354 | B | Inhibition of human TRPM2 expressed in HEK293T cells assessed as suppression of H2O2-induced calcium flux at 30 uM measured after 30 mins by Fluo-3/AM assay | Homo sapiens | 15 | ALA4834416 | cell-based format | Scientific Literature |