# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4135317 | B | Inhibition of BuChE (unknown origin) at 500 nM pre-incubated for 20 mins before S-Butyrylthiocholine iodide substrate addition by Ellman reagent based spectrophotometry | Homo sapiens | 11 | ALA4130501 | single protein format | Scientific Literature | |
2. | ALA4135318 | B | Inhibition of AChE (unknown origin) at 500 nM pre-incubated for 20 mins before acetylthiocholine iodide substrate addition by Ellman reagent based spectrophotometry | Homo sapiens | 11 | ALA4130501 | single protein format | Scientific Literature | |
3. | ALA4135319 | B | Inhibition of BuChE (unknown origin) pre-incubated for 20 mins before S-Butyrylthiocholine iodide substrate addition by Ellman reagent based spectrophotometry | Homo sapiens | 11 | ALA4130501 | single protein format | Scientific Literature | |
4. | ALA4135320 | B | Inhibition of self-induced amyloid beta (1 to 42) (unknown origin) aggregation at 10 uM after 24 hrs by thioflavin T-based fluorometric assay relative to control | Homo sapiens | 10 | ALA4130501 | single protein format | Scientific Literature | |
5. | ALA4135321 | F | Antioxidant activity assessed as DPPH radical scavenging activity incubated for 60 mins under dark condition by spectrophotometry | 10 | ALA4130501 | assay format | Scientific Literature | ||
6. | ALA4135322 | A | Permeability at 100 ug/ml incubated for 10 hrs by PAMPA method | 10 | ALA4130501 | assay format | Scientific Literature | ||
7. | ALA4135324 | A | Cytotoxicity in mouse HT22 cells assessed as reduction in cell viability at 30 to 100 uM incubated for 24 hrs by MTT assay | Mus musculus | 6 | ALA4130501 | cell-based format | Scientific Literature | |
8. | ALA4135329 | F | Neuroprotective activity against glutamate-induced cytotoxicity in mouse HT22 cells assessed as increase cell viability at 3 to 30 uM pre-incubated for 30 mins before glutamate stimulation for 24 hrs by MTT assay | Mus musculus | 3 | ALA4130501 | cell-based format | Scientific Literature |