# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4150966 | B | Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method | Homo sapiens | 26 | ALA4145652 | cell-based format | Scientific Literature | |
2. | ALA4150967 | B | Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method | Homo sapiens | 26 | ALA4145652 | cell-based format | Scientific Literature | |
3. | ALA4150968 | B | Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method | Homo sapiens | 26 | ALA4145652 | cell-based format | Scientific Literature | |
4. | ALA4150969 | B | Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method | Rattus norvegicus | 26 | ALA4145652 | cell-based format | Scientific Literature | |
5. | ALA4150970 | B | Substrate activity at human EAAT1 expressed in HEK293 cells assessed as increase in fluorescence level at 300 uM incubated for 30 mins by fluorescence-based FLIPR membrane potential blue assay | Homo sapiens | 10 | ALA4145652 | cell-based format | Scientific Literature | |
6. | ALA4150971 | B | Substrate activity at human EAAT2 expressed in HEK293 cells assessed as increase in fluorescence level at 300 uM incubated for 30 mins by fluorescence-based FLIPR membrane potential blue assay | Homo sapiens | 10 | ALA4145652 | cell-based format | Scientific Literature | |
7. | ALA4150972 | B | Substrate activity at human EAAT3 expressed in HEK293 cells assessed as increase in fluorescence level at 300 uM incubated for 30 mins by fluorescence-based FLIPR membrane potential blue assay | Homo sapiens | 10 | ALA4145652 | cell-based format | Scientific Literature | |
8. | ALA4150973 | B | Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in EC80 L-glutamate-induced response at 300 uM pre-incubated before L-glutamate addition by fluorescence-based FLIPR membrane potential blue assay | Homo sapiens | 10 | ALA4145652 | cell-based format | Scientific Literature | |
9. | ALA4150974 | B | Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in EC80 L-glutamate-induced response at 300 uM pre-incubated before L-glutamate addition by fluorescence-based FLIPR membrane potential blue assay | Homo sapiens | 10 | ALA4145652 | cell-based format | Scientific Literature | |
10. | ALA4150975 | B | Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in EC80 L-glutamate-induced response at 300 uM pre-incubated before L-glutamate addition by fluorescence-based FLIPR membrane potential blue assay | Homo sapiens | 10 | ALA4145652 | cell-based format | Scientific Literature | |
11. | ALA4150976 | B | Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in EC80 L-glutamate-induced response at 300 uM co-applied with L-glutamate addition by fluorescence-based FLIPR membrane potential blue assay | Homo sapiens | 10 | ALA4145652 | cell-based format | Scientific Literature | |
12. | ALA4150977 | B | Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in EC80 L-glutamate-induced response at 300 uM co-applied with L-glutamate addition by fluorescence-based FLIPR membrane potential blue assay | Homo sapiens | 10 | ALA4145652 | cell-based format | Scientific Literature | |
13. | ALA4150978 | B | Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in EC80 L-glutamate-induced response at 300 uM co-applied with L-glutamate addition by fluorescence-based FLIPR membrane potential blue assay | Homo sapiens | 10 | ALA4145652 | cell-based format | Scientific Literature |