# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4152680 | B | Displacement of [3H]CCPA from recombinant human adenosine A1 receptor transfected in CHO cell membranes after 3 hrs by microbeta scintillation counting analysis | Homo sapiens | 26 | ALA4152191 | cell-based format | Scientific Literature | |
2. | ALA4152681 | B | Displacement of [3H]NECA from recombinant human adenosine A2A receptor transfected in CHO cell membranes after 3 hrs by microbeta scintillation counting analysis | Homo sapiens | 26 | ALA4152191 | cell-based format | Scientific Literature | |
3. | ALA4152682 | F | Antagonist activity at recombinant human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-induced adenylyl cyclase activity after 20 mins by [alpha-32P]ATP assay | Homo sapiens | 26 | ALA4152191 | cell-based format | Scientific Literature | |
4. | ALA4152683 | B | Displacement of [3H]NECA from recombinant human adenosine A3 receptor transfected in CHO cell membranes after 3 hrs by microbeta scintillation counting analysis | Homo sapiens | 26 | ALA4152191 | cell-based format | Scientific Literature | |
5. | ALA4152684 | B | Selectivity index, ratio of Ki for recombinant human adenosine A2A receptor to Ki for recombinant human adenosine A1 receptor | Homo sapiens | 26 | ALA4152191 | assay format | Scientific Literature | |
6. | ALA4152685 | B | Selectivity index, ratio of Ki for recombinant human adenosine A2B receptor to Ki for recombinant human adenosine A1 receptor | Homo sapiens | 26 | ALA4152191 | assay format | Scientific Literature | |
7. | ALA4152686 | B | Selectivity index, ratio of Ki for recombinant human adenosine A3 receptor to Ki for recombinant human adenosine A1 receptor | Homo sapiens | 26 | ALA4152191 | assay format | Scientific Literature | |
8. | ALA4152687 | F | Antagonist activity at recombinant human adenosine A1 receptor transfected in CHO cells assessed as inhibition of CCPA-induced cAMP accumulation preincubated for 10 mins followed by CCPA addition by GloSensor cAMP assay | Homo sapiens | 6 | ALA4152191 | cell-based format | Scientific Literature | |
9. | ALA4152690 | F | Antagonist activity at adenosine A1 receptor in BALB/C mouse ileum assessed as reversal of CCPA-induced reduction in rhythmic spontaneous contractions at 1 uM after 1 hr | Mus musculus | 6 | ALA4152191 | assay format | Scientific Literature | |
10. | ALA4152692 | F | Activity at adenosine A1 receptor in BALB/C mouse ileum assessed as effect on amplitude of rhythmic spontaneous contractions at 1 uM after 1 hr | Mus musculus | 5 | ALA4152191 | assay format | Scientific Literature | |
11. | ALA4152693 | F | Activity at adenosine A1 receptor in BALB/C mouse ileum assessed as effect on frequency of rhythmic spontaneous contractions at 1 uM after 1 hr | Mus musculus | 5 | ALA4152191 | assay format | Scientific Literature |