| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4139285 | A | Inhibition of full length C-terminal FLAG tagged human SMS1 expressed in HEK293 cell membranes using DMPC-d72 and C17-ceramide as substrate preincubated for 60 mins followed by substrate addition measured after 30 mins by RapidFire/mass spectrometry assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA4139286 | B | Inhibition of full length C-terminal FLAG tagged human SMS2 expressed in HEK293 cell membranes using DMPC-d72 and C17-ceramide as substrate preincubated for 60 mins followed by substrate addition measured after 30 mins by RapidFire/mass spectrometry assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA4139287 | B | Selectivity index, ratio of IC50 for full length C-terminal FLAG tagged human SMS1 to IC50 for full length C-terminal FLAG tagged human SMS2 | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 4. | ALA4139294 | B | Inhibition of full length C-terminal FLAG tagged human SMS2 expressed in HEK293 cell membranes at 3 uM using DMPC-d72 and C17-ceramide as substrate preincubated for 60 mins followed by substrate addition measured after 30 mins by RapidFire/mass spectrometry assay | Homo sapiens | 3 | cell-based format | Scientific Literature |
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