| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4143325 | F | Antifilarial activity against Setaria cervi microfilariae after 24 hrs by MTT assay | Setaria cervi | 24 | organism-based format | Scientific Literature | ||
| 2. | ALA4143326 | F | Antifilarial activity against Setaria cervi adult after 24 hrs by MTT assay | Setaria cervi | 5 | organism-based format | Scientific Literature | ||
| 3. | ALA4143327 | F | Antifilarial activity against Setaria cervi oocytes after 24 hrs by MTT assay | Setaria cervi | 5 | organism-based format | Scientific Literature | ||
| 4. | ALA4143328 | F | Antifilarial activity against Setaria cervi microfilariae after 3 hrs by trypan blue exclusion assay | Setaria cervi | 6 | organism-based format | Scientific Literature | ||
| 5. | ALA4143329 | F | Antifilarial activity against Setaria cervi adult after 3 hrs by trypan blue exclusion assay | Setaria cervi | 5 | organism-based format | Scientific Literature | ||
| 6. | ALA4143330 | A | Cytotoxicity against human WI38 cells after 24 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA4143331 | T | Selectivity ratio of IC50 for human WI38 cells to IC50 for Setaria cervi microfilariae | 3 | assay format | Scientific Literature | |||
| 8. | ALA4143332 | F | Induction of reactive oxygen species generation in Setaria cervi adult form at 1 to 10 uM by NBT assay | Setaria cervi | 3 | organism-based format | Scientific Literature | ||
| 9. | ALA4143333 | F | Induction of reactive oxygen species generation in Setaria cervi microfilariae at 1 to 10 uM by NBT assay | Setaria cervi | 3 | organism-based format | Scientific Literature | ||
| 10. | ALA4143335 | F | Induction of chromatin condensation in Setaria cervi microfilariae at 5 ug/ml after 3 hrs by Hoechst 33342 staining-based phase contrast microscopic analysis | Setaria cervi | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA4143336 | F | Induction of apoptosis in Setaria cervi microfilariae at 1 to 5 ug/ml by acridine orange/ethidium bromide staining-based fluorescence microscopic analysis | Setaria cervi | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA4143337 | F | Induction of apoptosis in Setaria cervi oocytes at 1 to 5 ug/ml by acridine orange/ethidium bromide staining-based fluorescence microscopic analysis | Setaria cervi | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA4143338 | F | Induction of apoptosis in Setaria cervi microfilaria assessed as viable cells at 50 ug/ml after 6 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 97.66%) | Setaria cervi | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA4143339 | F | Induction of apoptosis in Setaria cervi microfilaria assessed as early apoptotic cells at 50 ug/ml after 6 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 2.11%) | Setaria cervi | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA4143340 | F | Induction of apoptosis in Setaria cervi microfilaria assessed as late apoptotic cells at 50 ug/ml after 6 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 0.21%) | Setaria cervi | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA4143341 | F | Induction of apoptosis in Setaria cervi microfilaria assessed as necrotic cells at 50 ug/ml after 6 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 0.02%) | Setaria cervi | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA4143342 | F | Induction of apoptosis in Setaria cervi oocytes assessed as viable cells at 50 ug/ml after 6 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 90.03%) | Setaria cervi | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA4143343 | F | Induction of apoptosis in Setaria cervi oocytes assessed as early apoptotic cells at 50 ug/ml after 6 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 8.19%) | Setaria cervi | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA4143344 | F | Induction of apoptosis in Setaria cervi oocytes assessed as late apoptotic cells at 50 ug/ml after 6 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 0.64%) | Setaria cervi | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA4143345 | F | Induction of apoptosis in Setaria cervi oocytes assessed as necrotic cells at 50 ug/ml after 6 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 1.14%) | Setaria cervi | 1 | organism-based format | Scientific Literature |
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