# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4202175 | B | Antagonist activity at rat alpha3beta4 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membrane currents pre-incubated for 5 mins prior to acetyl choline pulse at -70 mV potential by two-electrode voltage clamp assay | Rattus norvegicus | 15 | cell-based format | Scientific Literature | ||
2. | ALA4202177 | B | Antagonist activity at rat alpha6/alpha3beta4 nAChR nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membrane currents pre-incubated for 5 mins prior to acetyl choline pulse at -70 mV potential by two-electrode voltage clamp assay | Rattus norvegicus | 15 | cell-based format | Scientific Literature | ||
3. | ALA4202178 | B | Antagonist activity at rat alpha6/alpha3beta4 nAChR nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membrane currents at 10 uM pre-incubated for 5 mins prior to acetyl choline pulse at -70 mV potential by two-electrode voltage clamp assay | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
4. | ALA4202179 | B | Selectivity index, ratio of IC50 for antagonist activity at rat alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes to IC50 for antagonist activity at rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes | Rattus norvegicus | 15 | cell-based format | Scientific Literature |