| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4185346 | A | Substrate activity at CYP3A4 (unknown origin) assessed as enzyme-mediated compound turnover assessed per pmol protein at 10 uM | Homo sapiens | 12 | ALA4184142 | single protein format | Scientific Literature | |
| 2. | ALA4185347 | A | Substrate activity at CYP3A5 (unknown origin) assessed as enzyme-mediated compound turnover assessed per pmol protein at 10 uM | Homo sapiens | 12 | ALA4184142 | single protein format | Scientific Literature | |
| 3. | ALA4185348 | A | Substrate activity at CYP3A5 in human liver microsomes assessed as enzyme-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation preincubated for 3 mins followed by NADPH addition measured after 20 mins by UFLC-DAD analysis | Homo sapiens | 1 | ALA4184142 | microsome format | Scientific Literature | |
| 4. | ALA4185349 | A | Substrate activity at CYP3A5 in human liver microsomes assessed as enzyme-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation in presence of S-adenosyl-L-methionine by UFLC-DAD analysis | Homo sapiens | 1 | ALA4184142 | microsome format | Scientific Literature | |
| 5. | ALA4185350 | A | Substrate activity at CYP3A5 in human liver microsomes assessed as enzyme-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation in presence of UDP-glucuronic acid by UFLC-DAD analysis | Homo sapiens | 1 | ALA4184142 | microsome format | Scientific Literature | |
| 6. | ALA4185351 | A | Substrate activity at CYP3A5 in human liver microsomes assessed as enzyme-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation in presence of 3'-phosphoadenosine-5'-phosphosulfate by UFLC-DAD analysis | Homo sapiens | 1 | ALA4184142 | microsome format | Scientific Literature | |
| 7. | ALA4185352 | A | Substrate activity at recombinant human CYP3A4 expressed in bactosomes assessed as enzyme-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation at 5 to 50 uM after 30 mins in presence of NADPH by UFLC-DAD analysis | Homo sapiens | 1 | ALA4184142 | assay format | Scientific Literature | |
| 8. | ALA4185353 | A | Substrate activity at recombinant human CYP3A5 expressed in bactosomes assessed as CYP3A5-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation at 5 to 50 uM after 30 mins in presence of NADPH by UFLC-DAD analysis | Homo sapiens | 1 | ALA4184142 | assay format | Scientific Literature | |
| 9. | ALA4185354 | A | Substrate activity at CYP2A6 in human liver microsomes with NADPH-generating system assessed as CYP2A6-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation at 5 uM after 25 mins in presence of 8-methoxypsoralen | Homo sapiens | 1 | ALA4184142 | microsome format | Scientific Literature | |
| 10. | ALA4185355 | A | Substrate activity at recombinant human CYP1A1 expressed in bactosomes assessed as CYP1A1-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation at 5 to 50 uM after 30 mins in presence of NADPH by UFLC-DAD analysis | Homo sapiens | 1 | ALA4184142 | assay format | Scientific Literature | |
| 11. | ALA4185356 | A | Substrate activity at recombinant human CYP1A2 expressed in bactosomes assessed as CYP1A2-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation at 5 to 50 uM after 30 mins in presence of NADPH by UFLC-DAD analysis | Homo sapiens | 1 | ALA4184142 | assay format | Scientific Literature | |
| 12. | ALA4185357 | A | Substrate activity at recombinant human CYP1B1 expressed in bactosomes assessed as CYP1B1-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation at 5 to 50 uM after 30 mins in presence of NADPH by UFLC-DAD analysis | Homo sapiens | 1 | ALA4184142 | assay format | Scientific Literature | |
| 13. | ALA4185358 | A | Substrate activity at recombinant human CYP2A6 expressed in bactosomes assessed as CYP2A6-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation at 5 to 50 uM after 30 mins in presence of NADPH by UFLC-DAD analysis | Homo sapiens | 1 | ALA4184142 | assay format | Scientific Literature | |
| 14. | ALA4185359 | A | Substrate activity at recombinant human CYP2B6 expressed in bactosomes assessed as CYP2B6-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation at 5 to 50 uM after 30 mins in presence of NADPH by UFLC-DAD analysis | Homo sapiens | 1 | ALA4184142 | assay format | Scientific Literature | |
| 15. | ALA4185360 | A | Substrate activity at recombinant human CYP2C8 expressed in bactosomes assessed as CYP2C8-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation at 5 to 50 uM after 30 mins in presence of NADPH by UFLC-DAD analysis | Homo sapiens | 1 | ALA4184142 | assay format | Scientific Literature | |
| 16. | ALA4185361 | A | Substrate activity at recombinant human CYP2C9 expressed in bactosomes assessed as CYP2C9-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation at 5 to 50 uM after 30 mins in presence of NADPH by UFLC-DAD analysis | Homo sapiens | 1 | ALA4184142 | assay format | Scientific Literature | |
| 17. | ALA4185362 | A | Substrate activity at recombinant human CYP2C19 expressed in bactosomes assessed as CYP2C19-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation at 5 to 50 uM after 30 mins in presence of NADPH by UFLC-DAD analysis | Homo sapiens | 1 | ALA4184142 | assay format | Scientific Literature | |
| 18. | ALA4185363 | A | Substrate activity at recombinant human CYP2D6 expressed in bactosomes assessed as CYP2D6-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation at 5 to 50 uM after 30 mins in presence of NADPH by UFLC-DAD analysis | Homo sapiens | 1 | ALA4184142 | assay format | Scientific Literature | |
| 19. | ALA4185364 | A | Substrate activity at recombinant human CYP2E1 expressed in bactosomes assessed as CYP2E1-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation at 5 to 50 uM after 30 mins in presence of NADPH by UFLC-DAD analysis | Homo sapiens | 1 | ALA4184142 | assay format | Scientific Literature | |
| 20. | ALA4185365 | A | Substrate activity at recombinant human CYP2J2 expressed in bactosomes assessed as CYP2J2-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation at 5 to 50 uM after 30 mins in presence of NADPH by UFLC-DAD analysis | Homo sapiens | 1 | ALA4184142 | assay format | Scientific Literature |
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