# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4194391 | Functional | Antiviral activity against HIV1 3B infected in human MT4 cells assessed as inhibition of virus-induced cytopathogenicity by measuring virus-induced syncytium formation by MTT assay | Human immunodeficiency virus 1 | 25 | ALA4190364 | organism-based format | Scientific Literature | |
2. | ALA4194392 | Functional | Antiviral activity against HIV2 ROD infected in human MT4 cells assessed as inhibition of virus-induced cytopathogenicity by measuring virus-induced syncytium formation by MTT assay | Human immunodeficiency virus 2 | 21 | ALA4190364 | organism-based format | Scientific Literature | |
3. | ALA4194393 | Functional | Antiviral activity against HIV1 RES056 expressing reverse transcriptase K103N/Y181C double mutant infected in human MT4 cells assessed as inhibition of virus-induced cytopathogenicity by measuring virus-induced syncytium formation by MTT assay | Human immunodeficiency virus 1 | 24 | ALA4190364 | organism-based format | Scientific Literature | |
4. | ALA4194394 | ADME | Cytotoxicity in mock-infected human MT4 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 25 | ALA4190364 | cell-based format | Scientific Literature | |
5. | ALA4194395 | Toxicity | Selectivity index, ratio of CC50 for mock-infected human MT4 cells to EC50 for antiviral activity against HIV1 3B infected in human MT4 cells | 25 | ALA4190364 | cell-based format | Scientific Literature | ||
6. | ALA4194396 | Binding | Inhibition of recombinant wild type HIV1 reverse transcriptase p66/p51 assessed as reduction in biotin-dUTP incorporation incubated for 40 mins using poly(rA) template and oligo(dT)16 primer by picogreen dye based spectrofluorometry | Human immunodeficiency virus 1 | 14 | ALA4190364 | single protein format | Scientific Literature |