#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4189496	B	Inhibition of GST-tagged MNK1 (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubated for 10 mins followed by substrate and ATP addition measured after 60 mins	Homo sapiens	26		assay format	Scientific Literature
2.	ALA4189497	B	Inhibition of GST-tagged MNK2 (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubated for 10 mins followed by substrate and ATP addition measured after 60 mins	Homo sapiens	26		assay format	Scientific Literature
3.	ALA4189498	B	Inhibition of MNK1/2 in human HeLa cells assessed as decrease in eIF4E phosphorylation at Ser209 after 2 hrs by AlphaScreen assay	Homo sapiens	24		cell-based format	Scientific Literature
4.	ALA4189499	P	Octanol-phosphate buffer partition coefficient, logD of compound at pH 7.4 by HPLC-UV analysis		19		small-molecule physicochemical format	Scientific Literature
5.	ALA4189500	A	Permeability of the compound by PAMPA		19		assay format	Scientific Literature
6.	ALA4189501	A	Half life in human liver microsomes at 1 uM in presence of NADPH by LC-MS/MS analysis	Homo sapiens	10		microsome format	Scientific Literature
7.	ALA4189502	A	Half life in mouse liver microsomes at 1 uM in presence of NADPH by LC-MS/MS analysis	Mus musculus	10		microsome format	Scientific Literature
8.	ALA4189503	A	Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins followed by NADPH addition measured after 5 mins by LC-MS/MS analysis	Homo sapiens	9		microsome format	Scientific Literature
9.	ALA4189504	A	Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate preincubated for 5 mins followed by NADPH addition by LC-MS/MS analysis	Homo sapiens	8		microsome format	Scientific Literature
10.	ALA4189505	P	Thermodynamic solubility of the compound at pH 4 to 7.4 pION buffer after 18 hrs by UV spectrophotometric analysis		18		small-molecule physicochemical format	Scientific Literature
11.	ALA4189506	A	Half life in rat liver microsomes at 1 uM in presence of NADPH by LC-MS/MS analysis	Rattus norvegicus	2		microsome format	Scientific Literature
12.	ALA4189507	A	Half life in dog liver microsomes at 1 uM in presence of NADPH by LC-MS/MS analysis	Canis lupus familiaris	2		microsome format	Scientific Literature
13.	ALA4189508	A	Apparent permeability of the compound across apical side to basolateral side in human Caco2 cells by LC-MS/MS analysis	Homo sapiens	9		cell-based format	Scientific Literature
14.	ALA4189509	A	Efflux ratio of apparent permeability in human Caco2 cells by LC-MS/MS analysis	Homo sapiens	9		cell-based format	Scientific Literature
15.	ALA4189510	A	Protein binding in human plasma at 1 mM after 5 hrs by LC-MS/MS analysis	Homo sapiens	5		cell-free format	Scientific Literature
16.	ALA4189511	A	Protein binding in mouse plasma at 1 mM after 5 hrs by LC-MS/MS analysis	Mus musculus	5		cell-free format	Scientific Literature
17.	ALA4189512	A	Initial concentration in CD-1 mouse at 1 mg/kg, iv administered as single dose by LC-MS/MS analysis	Mus musculus	2		organism-based format	Scientific Literature
18.	ALA4189513	A	AUClast in CD-1 mouse at 5 mg/kg, po administered via gavage as single dose by LC-MS/MS analysis	Mus musculus	3		organism-based format	Scientific Literature
19.	ALA4189514	A	AUClast in CD-1 mouse at 1 mg/kg, iv administered as single dose by LC-MS/MS analysis	Mus musculus	2		organism-based format	Scientific Literature
20.	ALA4189515	A	Cmax in CD-1 mouse at 5 mg/kg, po administered via gavage as single dose by LC-MS/MS analysis	Mus musculus	3		organism-based format	Scientific Literature