# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4183223 | F | Hypolipidemic activity in ob/ob mouse assessed as decrease in macrosteatosis at 3 mg/kg administered daily via oral gavage for 31 days by hematoxylin-eosin staining-based microscopic method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
2. | ALA4183224 | B | Inhibition of pig liver microsomal HMG-CoA reductase by colorimetric method | Sus scrofa | 16 | assay format | Scientific Literature | ||
3. | ALA4183225 | B | Inhibition of rat small intestinal mucosal alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate after 40 mins by colorimetric method | Rattus norvegicus | 16 | assay format | Scientific Literature | ||
4. | ALA4183226 | B | Inhibition of rat small intestinal mucosal alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate by HPLC method | Rattus norvegicus | 4 | assay format | Scientific Literature | ||
5. | ALA4183227 | P | Chemical stability of the compound at 0.4 mg/ml at room temperature after 3 weeks by HPLC method | 1 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA4183228 | T | Toxicity in C57BL/6J mouse assessed as effect on behavior at 30 mg/kg administered daily via oral gavage for 3 months | Mus musculus | 1 | organism-based format | Scientific Literature | ||
7. | ALA4183229 | T | Toxicity in C57BL/6J mouse assessed as effect on body weight at 30 mg/kg administered daily via oral gavage for 3 months | Mus musculus | 1 | organism-based format | Scientific Literature | ||
8. | ALA4183230 | T | Toxicity in C57BL/6J mouse assessed as effect on free diet blood glucose levels at 30 mg/kg administered daily via oral gavage for 3 months | Mus musculus | 1 | organism-based format | Scientific Literature | ||
9. | ALA4183231 | T | Toxicity in C57BL/6J mouse assessed as effect on plasma AST levels at 30 mg/kg administered daily via oral gavage for 3 months | Mus musculus | 1 | organism-based format | Scientific Literature | ||
10. | ALA4183232 | T | Toxicity in C57BL/6J mouse assessed as effect on plasma ALT levels at 30 mg/kg administered daily via oral gavage for 3 months | Mus musculus | 1 | organism-based format | Scientific Literature | ||
11. | ALA4183233 | T | Toxicity in C57BL/6J mouse assessed as effect on organ coefficients at 30 mg/kg administered daily via oral gavage for 3 months | Mus musculus | 1 | organism-based format | Scientific Literature | ||
12. | ALA4183234 | T | Toxicity in C57BL/6J mouse assessed as effect on survival at 30 mg/kg administered daily via oral gavage for 3 months | Mus musculus | 1 | organism-based format | Scientific Literature | ||
13. | ALA4183235 | A | Cmax in Sprague-Dawley rat at 2 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
14. | ALA4183236 | A | Tmax in Sprague-Dawley rat at 2 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
15. | ALA4183237 | A | AUC (0 to t) in Sprague-Dawley rat at 2 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
16. | ALA4183238 | A | Half life in Sprague-Dawley rat at 2 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
17. | ALA4183239 | A | AUC (0 to infinity) in Sprague-Dawley rat at 2 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
18. | ALA4183240 | F | Antiobesity activity in ob/ob mouse assessed as reduction in weight gain at 3 mg/kg administered daily via oral gavage for 31 days relative to vehicle-treated control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
19. | ALA4183241 | F | Antiobesity activity in ob/ob mouse assessed as reduction in cumulative food intake at 3 mg/kg administered daily via oral gavage for 25 days relative to vehicle-treated control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
20. | ALA4183242 | F | Antiobesity activity in ob/ob mouse assessed as reduction in LEE index at 3 mg/kg administered daily via oral gavage for 31 days relative to vehicle-treated control | Mus musculus | 1 | organism-based format | Scientific Literature |