# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4192100 | B | Modulation of [3H]NCS-382 binding to alpha4betadelta GABAA receptor in rat cortical membranes after 1 hr by TopCount scintillation counting method | Rattus norvegicus | 42 | ALA4190247 | cell membrane format | Scientific Literature | |
2. | ALA4192101 | B | Modulation of [3H]NCS-382 binding to alpha4betadelta GABAA receptor in rat cortical membranes assessed as [3H]NCS-382 binding at 100 uM after 1 hr by TopCount scintillation counting method relative to control | Rattus norvegicus | 40 | ALA4190247 | cell membrane format | Scientific Literature | |
3. | ALA4192102 | B | Modulation of human alpha1beta2delta GABAA receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-induced current at 1 mM at -60 mV holding potential by two-electrode voltage clamp electrophysiology method relative to control | Homo sapiens | 7 | ALA4190247 | cell-based format | Scientific Literature | |
4. | ALA4192103 | B | Agonist activity at human alpha1beta2delta GABAA receptor expressed in Xenopus laevis oocytes assessed as increase in current amplitude at 1 mM at -60 mV holding potential by two-electrode voltage clamp electrophysiology method | Homo sapiens | 7 | ALA4190247 | cell-based format | Scientific Literature | |
5. | ALA4192104 | B | Modulation of human alpha1beta2delta GABAA receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-induced current by measuring rebound current at 1 mM at -60 mV holding potential measured after termination of compound application by two-electrode voltage clamp electrophysiology method relative to control | Homo sapiens | 4 | ALA4190247 | cell-based format | Scientific Literature | |
6. | ALA4192105 | B | Modulation of human alpha1beta2 GABAA receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-induced current at 1 mM at -60 mV holding potential by two-electrode voltage clamp electrophysiology method | Homo sapiens | 7 | ALA4190247 | cell-based format | Scientific Literature | |
7. | ALA4192106 | B | Modulation of human alpha1beta2gamma2S GABAA receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-induced current at 1 mM at -60 mV holding potential by two-electrode voltage clamp electrophysiology method | Homo sapiens | 7 | ALA4190247 | cell-based format | Scientific Literature |