# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4199595 | Functional | Antileishmanial activity against Leishmania infantum MHOM/TN/80/IPT1 promastigotes after 72 hrs by MTT assay | Leishmania infantum | 31 | ALA4196114 | organism-based format | Scientific Literature | |
2. | ALA4199596 | Functional | Antileishmanial activity against Leishmania tropica MHOM/IT/2012/ISS3130 promastigotes after 72 hrs by MTT assay | Leishmania tropica | 31 | ALA4196114 | organism-based format | Scientific Literature | |
3. | ALA4199597 | ADME | Cytotoxicity against PMA-differentiated human THP1 cells after 72 hrs by MTT assay | Homo sapiens | 31 | ALA4196114 | cell-based format | Scientific Literature | |
4. | ALA4199598 | Toxicity | Selectivity index, ratio of IC50 for PMA-differentiated human THP1 cells to IC50 for Leishmania infantum MHOM/TN/80/IPT1 promastigotes | 31 | ALA4196114 | assay format | Scientific Literature | ||
5. | ALA4199599 | Toxicity | Selectivity index, ratio of IC50 for PMA-differentiated human THP1 cells to IC50 for Leishmania tropica MHOM/IT/2012/ISS3130 promastigotes | 31 | ALA4196114 | assay format | Scientific Literature | ||
6. | ALA4199600 | Functional | Antileishmanial activity against amastigote stage of Leishmania infantum infected in PMA-differentiated human THP1 cells assessed as inhibition of parasite growth at 0.5 uM after 72 hrs by Giemsa staining based light microscopy relative to control | Leishmania infantum | 11 | ALA4196114 | organism-based format | Scientific Literature | |
7. | ALA4199601 | Functional | Antileishmanial activity against amastigote stage of Leishmania infantum infected in PMA-differentiated human THP1 cells assessed as inhibition of parasite growth after 72 hrs by Giemsa staining based light microscopy | Leishmania infantum | 11 | ALA4196114 | organism-based format | Scientific Literature | |
8. | ALA4199602 | Toxicity | Selectivity index, ratio of IC50 for PMA-differentiated human THP1 cells to IC50 for amastigote stage of Leishmania infantum infected in PMA-differentiated human THP1 cells | 11 | ALA4196114 | assay format | Scientific Literature |