# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4190815 | Functional | Cytotoxicity against human LN18 cells harboring TP53 mutation assessed as cell death at 20 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 16 | ALA4190186 | cell-based format | Scientific Literature | |
2. | ALA4190817 | Functional | Cytotoxicity against PTEN/TP53 deficient human T98G cells assessed as cell death at 20 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 16 | ALA4190186 | cell-based format | Scientific Literature | |
3. | ALA4483863 | Functional | Luciferase/luciferin-expressing antifolate-resistant parasites were used to infect a culture of HepG2 cells that were pre-incubated with compounds. Infected hepatocytes emit light due to the luciferase reaction. Assay results are presented as the percent inhibition of light emission compared to control. (Single Point Inhibition, %) | Plasmodium berghei | 9,989 | ALA4483862 | organism-based format | Winzeler Lab Plasmodium Screening Data | |
4. | ALA4483864 | Functional | Luciferase/luciferin-expressing antifolate-resistant parasites were used to infect a culture of HepG2 cells that were pre-incubated with compounds. Infected hepatocytes emit light due to the luciferase reaction. Assay results are presented as the percent inhibition of light emission compared to control. (Single Point Inhibition, %) | Homo sapiens | 9,989 | ALA4483862 | cell-based format | Winzeler Lab Plasmodium Screening Data |