# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4199826 | B | Binding affinity to hemoglobin (unknown origin) assessed as increase in release of carbon monooxide from carboxyhemoglobin by measuring half life of carboxyhemoglobin at 20:1 compound/Hb tetramer ratio incubated for 1 hr measured every 15 mins for 90 mins (Rvb = 80 +/- 0.3 min) | Homo sapiens | 11 | protein complex format | Scientific Literature | ||
2. | ALA4199827 | B | Binding affinity to hemoglobin (unknown origin) assessed as increase in release of carbon monooxide from carboxyhemoglobin by measuring half life of carboxyhemoglobin at 5:1 compound/Hb tetramer ratio incubated for 1 hr measured every 15 mins for 90 mins (Rvb = 80 +/- 0.3 min) | Homo sapiens | 11 | protein complex format | Scientific Literature | ||
3. | ALA4199829 | A | Hemolytic activity against human RBC assessed as increase in fraction of extracellular Hb level at 1 mM after 1 hr | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA4199830 | P | Aqueous solubility of the compound in DMSO/H2O2 solution at 2.5 mM | 11 | small-molecule physicochemical format | Scientific Literature |