# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4190484 | B | Proteolysis targeting chimera activity in human THP1 cells assessed as induction of VHL-mediated delivery of RIPK2 for protein degradation by proteasome by measuring drug level causing 50% substrate depletion incubated for 16 hrs by Western blot method | Homo sapiens | 1 | ALA4190166 | cell-based format | Scientific Literature | |
2. | ALA4190485 | B | Proteolysis targeting chimera activity in human THP1 cells assessed as induction of VHL-mediated delivery of RIPK2 for protein degradation by proteasome at >10 nM incubated for 16 hrs by Western blot method relative to control | Homo sapiens | 1 | ALA4190166 | cell-based format | Scientific Literature | |
3. | ALA4190486 | B | Binding affinity to MAPKAPK3 (unknown origin) | Homo sapiens | 1 | ALA4190166 | single protein format | Scientific Literature |