# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4199270 | Binding | Displacement of [3H]5-CT from rat 5-HT7 receptor expressed in HEK293 cell membranes by radioligand binding assay | Rattus norvegicus | 1 | ALA4196098 | cell-based format | Scientific Literature | |
2. | ALA4343397 | Binding | Antagonist activity at 5-HT1A receptor (unknown origin) | Homo sapiens | 22 | ALA4342419 | single protein format | Scientific Literature | |
3. | ALA4343398 | Binding | Displacement of [3H]5-CT from recombinant rat 5-HT7 receptor expressed in HEK293 cells | Rattus norvegicus | 1 | ALA4342419 | cell-based format | Scientific Literature | |
4. | ALA4651403 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 4,309 | ALA4651402 | organism-based format | IMI-CARE SARS-CoV-2 Data | |
5. | ALA4651404 | Functional | Determination of IC50 values for inhibition of SARS-CoV-2 induced cytotoxicity of VERO-E6 cells after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 244 | ALA4651402 | organism-based format | IMI-CARE SARS-CoV-2 Data | |
6. | ALA4651405 | Toxicity | Toxicity CC50 against VERO-E6 cells determined at 48 hours by high content imaging (same conditions as IC50 assay without exposure to 0.01 MOI SARS CoV-2 virus) | Chlorocebus sabaeus | 222 | ALA4651402 | cell-based format | IMI-CARE SARS-CoV-2 Data | |
7. | ALA4677345 | Binding | Displacement of [3H]-ketanserin from human 5-HT2A receptor by competitive radioligand binding assay | Homo sapiens | 19 | ALA4673280 | single protein format | Scientific Literature | |
8. | ALA4677346 | Binding | Displacement of [3H]-CT from rat 5-HT7 receptor expressed in HEK293 cells by competitive radioligand binding assay | Rattus norvegicus | 19 | ALA4673280 | cell-based format | Scientific Literature | |
9. | ALA5215977 | Binding | Binding affinity to 5-HT7R (unknown origin) assessed as inhibition constant | Homo sapiens | 7 | ALA5214911 | single protein format | Scientific Literature |