# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4198087 | B | Inhibition of recombinant Leishmania infantum trypanothione reductase using T[S]2 as substrate preincubated for 5 mins followed by substrate and NADPH addition measured for 1 hr | Leishmania infantum | 5 | ALA4196062 | single protein format | Scientific Literature | |
2. | ALA4198088 | B | Inhibition of dimerization of HIS/FLAG tagged Leishmania infantum trypanothione reductase incubated for 16 hrs by ELISA | Leishmania infantum | 3 | ALA4196062 | single protein format | Scientific Literature | |
3. | ALA4198090 | A | Drug metabolism assessed as Tritirachium album proteinase K-mediated compound degradation by measuring half life at 100 uM measured up to 360 mins by HPLC method | Parengyodontium album | 1 | ALA4196062 | single protein format | Scientific Literature | |
4. | ALA4198097 | B | Inhibition of dimerization of HIS/FLAG tagged Leishmania infantum trypanothione reductase assessed as dimer levels at 9.375 uM incubated for 16 hrs by ELISA (Rvb = 100%) | Leishmania infantum | 4 | ALA4196062 | single protein format | Scientific Literature | |
5. | ALA4198098 | B | Inhibition of dimerization of HIS/FLAG tagged Leishmania infantum trypanothione reductase assessed as dimer levels at 18.75 uM incubated for 16 hrs by ELISA (Rvb = 100%) | Leishmania infantum | 4 | ALA4196062 | single protein format | Scientific Literature | |
6. | ALA4198099 | B | Inhibition of dimerization of HIS/FLAG tagged Leishmania infantum trypanothione reductase assessed as dimer levels at 37.5 uM incubated for 16 hrs by ELISA (Rvb = 100%) | Leishmania infantum | 4 | ALA4196062 | single protein format | Scientific Literature | |
7. | ALA4198100 | B | Inhibition of dimerization of HIS/FLAG tagged Leishmania infantum trypanothione reductase assessed as dimer levels at 75 uM incubated for 16 hrs by ELISA (Rvb = 100%) | Leishmania infantum | 4 | ALA4196062 | single protein format | Scientific Literature |