| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4182255 | A | Inhibition of recombinant human BRD2 bromodomain 1 (49 to 170 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by substrate addition measured after 1 hr by TR-FRET assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 2. | ALA4182256 | B | Inhibition of recombinant human BRD2 bromodomain 2 (342 to 460 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by substrate addition measured after 1 hr by TR-FRET assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 3. | ALA4182257 | B | Selectivity index, ratio of IC50 for recombinant human BRD2 bromodomain 1 (49 to 170 residues) to IC50 for recombinant human BRD2 bromodomain 2 (342 to 460 residues) | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 4. | ALA4182258 | A | Binding affinity to His-tagged BRD2 bromodomain 1 (unknown origin) by SPR assay | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 5. | ALA4182259 | B | Binding affinity to His-tagged BRD2 bromodomain 2 (unknown origin) by SPR assay | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 6. | ALA4182260 | B | Selectivity index, ratio of Kd for His-tagged BRD2 bromodomain 1 (unknown origin) to Kd for His-tagged BRD2 bromodomain 2 (unknown origin) | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 7. | ALA4182261 | A | Binding affinity to BRD2 bromodomain 1 (74 to 194 residues) (unknown origin) by ITC | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 8. | ALA4182262 | B | Binding affinity to BRD2 bromodomain 2 (348 to 455 residues) (unknown origin) by ITC | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 9. | ALA4182263 | B | Selectivity index, ratio of Kd for BRD2 bromodomain 1 (74 to 194 residues) (unknown origin to Kd for BRD2 bromodomain 2 (348 to 455 residues) (unknown origin) | Homo sapiens | 7 | assay format | Scientific Literature |
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