| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4201103 | B | Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins | Mycobacterium tuberculosis H37Rv | 13 | assay format | Scientific Literature | ||
| 2. | ALA4201104 | B | Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpA expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins | Mycobacterium tuberculosis H37Rv | 8 | assay format | Scientific Literature | ||
| 3. | ALA4201105 | B | Inhibition of human PTP1B using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 4. | ALA4201106 | B | Inhibition of human VHR using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 5. | ALA4201108 | B | Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB H94A mutant expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins | Mycobacterium tuberculosis H37Rv | 5 | assay format | Scientific Literature | ||
| 6. | ALA4201109 | B | Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB E129A mutant expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins | Mycobacterium tuberculosis H37Rv | 5 | assay format | Scientific Literature | ||
| 7. | ALA4201110 | B | Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB R136A mutant expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins | Mycobacterium tuberculosis H37Rv | 5 | assay format | Scientific Literature | ||
| 8. | ALA4201123 | A | Cmax in Dunkin Hartley guinea pig at 2.5 mg/kg, ip after 0.5 hrs post dose | Cavia porcellus | 2 | organism-based format | Scientific Literature | ||
| 9. | ALA4201124 | A | Half life in Dunkin Hartley guinea pig at 2.5 mg/kg, ip | Cavia porcellus | 2 | organism-based format | Scientific Literature | ||
| 10. | ALA4201125 | A | AUCinfinity in Dunkin Hartley guinea pig at 2.5 mg/kg, ip | Cavia porcellus | 2 | organism-based format | Scientific Literature | ||
| 11. | ALA4201126 | A | Cmax in Dunkin Hartley guinea pig at 5 mg/kg, po after 0.25 hrs post dose | Cavia porcellus | 2 | organism-based format | Scientific Literature | ||
| 12. | ALA4201127 | A | Half life in Dunkin Hartley guinea pig at 5 mg/kg, po | Cavia porcellus | 2 | organism-based format | Scientific Literature | ||
| 13. | ALA4201128 | A | AUCinfinity in Dunkin Hartley guinea pig at 5 mg/kg, po | Cavia porcellus | 2 | organism-based format | Scientific Literature | ||
| 14. | ALA4201129 | A | Oral bioavailability in Dunkin Hartley guinea pig at 5 mg/kg | Cavia porcellus | 2 | organism-based format | Scientific Literature |
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