# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4187700 | F | Antiinflammatory activity in African green monkey CV1 cells assessed as inhibition of LPS-induced TNF-alpha production pre-incubated for 1 hr before LPS stimulation for 23 hrs by ELISA method | Chlorocebus aethiops | 4 | ALA4184223 | cell-based format | Scientific Literature | |
2. | ALA4187701 | F | Neuroprotective activity against amyloid beta (1 to 42) peptide-induced cytotoxicty in CD1 mouse primary cortical neurons assessed as increase in cell viability at 0.01 to 1 nM pre-incubated for 1 hr before amyloid beta (1 to 42) addition and measured after 24 hrs by CCK8 assay | Mus musculus | 3 | ALA4184223 | cell-based format | Scientific Literature | |
3. | ALA4187704 | T | Toxicity in CD1 mouse primary cortical neurons assessed as effect on cell viability at =< 10 nM incubated for 24 hrs by CCK8 assay | Mus musculus | 1 | ALA4184223 | cell-based format | Scientific Literature | |
4. | ALA4187705 | T | Toxicity in CD1 mouse primary cortical neurons assessed as effect on cell viability at 25 nM incubated for 24 hrs by CCK8 assay | Mus musculus | 2 | ALA4184223 | cell-based format | Scientific Literature | |
5. | ALA4187706 | T | Toxicity in CD1 mouse primary cortical neurons assessed as effect on cell viability at 50 nM incubated for 24 hrs by CCK8 assay | Mus musculus | 2 | ALA4184223 | cell-based format | Scientific Literature | |
6. | ALA4187707 | T | Toxicity in CD1 mouse primary cortical neurons assessed as effect on cell viability at 100 nM incubated for 24 hrs by CCK8 assay | Mus musculus | 2 | ALA4184223 | cell-based format | Scientific Literature | |
7. | ALA4187708 | T | Toxicity in African green monkey CV1 cells assessed as effect on cell viability incubated for 24 hrs by CCK8 assay | Chlorocebus aethiops | 6 | ALA4184223 | cell-based format | Scientific Literature | |
8. | ALA4187709 | F | Neuroprotective activity against amyloid beta (1 to 42) peptide-induced cytotoxicty in CD1 mouse primary cortical neurons assessed as increase in cell viability at 0.01 nM pre-incubated for 1 hr before amyloid beta (1 to 42) addition and measured after 24 hrs by CCK8 assay | Mus musculus | 2 | ALA4184223 | cell-based format | Scientific Literature | |
9. | ALA4187713 | P | Stability in neurobasal cell culture medium supplemented with B-27 and N2 assessed as compound hydrolysis by LC-HR MS method | 2 | ALA4184223 | small-molecule physicochemical format | Scientific Literature | ||
10. | ALA4187715 | F | Antiinflammatory activity in African green monkey CV1 cells assessed as inhibition of LPS-induced TNF-alpha production at 10 nM pre-incubated for 1 hr before LPS stimulation for 23 hrs by ELISA method | Chlorocebus aethiops | 1 | ALA4184223 | cell-based format | Scientific Literature |