| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4201437 | B | Binding affinity to MERS-CoV spike protein synthetic peptide HR1P at 75 uM incubated for 30 mins by Coomassie blue R250 staining based native polyacrylamide gel electrophoresis method | Middle East respiratory syndrome-related coronavirus | 1 | assay format | Scientific Literature | ||
| 2. | ALA4201438 | B | Inhibition of MERS-CoV spike protein-mediated cell-cell fusion in 293T/MERS/EGPF cells assessed as reduction in cell fusion incubated for 4 hrs by inverted fluorescence microscopy | Middle East respiratory syndrome-related coronavirus | 13 | cell-based format | Scientific Literature | ||
| 3. | ALA4201439 | A | Cytotoxicity in human HuH7 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 4. | ALA4201440 | F | Antiviral activity against Influenza A virus (A/Puerto Rico/8/1934(H1N1)) infected in HEK293T cells assessed as inhibition of viral replicon activity incubated for 30 hrs by dual-Glo luciferase assay | Influenza A virus | 5 | organism-based format | Scientific Literature | ||
| 5. | ALA4201441 | F | Antiviral activity against influenza A virus Hong Kong/8/1968(H3N2) infected in HEK293T cells assessed as inhibition of viral replicon activity incubated for 30 hrs by dual-Glo luciferase assay | Influenza A virus | 5 | organism-based format | Scientific Literature | ||
| 6. | ALA4201442 | A | Cytotoxicity in MDCK cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer-Glo cell viability assay | Canis lupus familiaris | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA4201443 | T | Selectivity index, ratio of CC50 for cytotoxicity in MDCK cells to EC50 for antiviral activity against Influenza A virus (A/Puerto Rico/8/1934(H1N1)) infected in HEK293T cells | 1 | cell-based format | Scientific Literature | |||
| 8. | ALA4201444 | T | Selectivity index, ratio of CC50 for cytotoxicity in MDCK cells to EC50 for antiviral activity against Influenza A virus (A/Hong Kong/8/1968(H2N2)) infected in HEK293T cells | 1 | cell-based format | Scientific Literature | |||
| 9. | ALA4201445 | F | Antiviral activity against oseltamivir-resistant Influenza A virus (H1N1) LN/1109 | Influenza A virus (H1N1) | 2 | organism-based format | Scientific Literature | ||
| 10. | ALA4201446 | F | Antiviral activity against oseltamivir-resistant Influenza A virus (H1N1) TJ/15 | Influenza A virus (H1N1) | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA4201451 | F | Antiviral activity against influenza A virus assessed as inhibition of viral replicon activity up to 100 uM incubated for 30 hrs by firefly luciferase reporter gene assay | Influenza A virus | 2 | organism-based format | Scientific Literature | ||
| 12. | ALA4201452 | F | Inhibition of Influenza A virus (A/Puerto Rico/8/1934(H1N1)) neuraminidase at 0.1 to 1000 uM by chemiluminescence based assay | Influenza A virus | 3 | organism-based format | Scientific Literature | ||
| 13. | ALA4201453 | F | Inhibition of influenza A virus Hong Kong/8/1968(H3N2) neuraminidase at 0.1 to 1000 uM by chemiluminescence based assay | Influenza A virus | 3 | organism-based format | Scientific Literature | ||
| 14. | ALA4201454 | F | Inhibition of influenza A virus infected in MDCK cells assessed as inhibition of viral load treated with compound at 0 to 10 hrs post-infection by RT-qPCR method based time of addition assay | Influenza A virus | 2 | organism-based format | Scientific Literature | ||
| 15. | ALA4201455 | F | Inhibition of influenza A virus infected in MDCK cells assessed as inhibition of viral load treated with compound at 0 to 2 hrs post-infection by RT-qPCR method based time of addition assay | Influenza A virus | 2 | organism-based format | Scientific Literature | ||
| 16. | ALA4201456 | F | Inhibition of influenza A virus infected in MDCK cells assessed as inhibition of viral load treated with compound at 2 to 5 hrs post-infection by RT-qPCR method based time of addition assay | Influenza A virus | 2 | organism-based format | Scientific Literature | ||
| 17. | ALA4201457 | F | Inhibition of influenza A virus infected in MDCK cells assessed as inhibition of viral load treated with compound at 5 to 8 hrs post-infection by RT-qPCR method based time of addition assay | Influenza A virus | 2 | organism-based format | Scientific Literature | ||
| 18. | ALA4201458 | F | Inhibition of influenza A virus infected in MDCK cells assessed as inhibition of viral load treated with compound at 8 to 10 hrs post-infection by RT-qPCR method based time of addition assay | Influenza A virus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA4201459 | B | Inhibition of Influenza A virus (A/Puerto Rico/8/1934(H1N1)) Hemagglutinin 1-induced aggregation of chicken erythrocytes at 0.05 to 100 uM | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 1 | assay format | Scientific Literature | ||
| 20. | ALA4201460 | B | Inhibition of Influenza A virus (A/Puerto Rico/8/1934(H1N1)) Hemagglutinin 2-mediated hemolysis of chicken erythrocytes at acidic pH conditions | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 1 | assay format | Scientific Literature |
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