| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4191523 | F | Antiproliferative activity against human PC3 cells assessed as decrease in cell viability after 3 days by WST assay | Homo sapiens | 35 | ALA4190216 | cell-based format | Scientific Literature | |
| 2. | ALA4191524 | F | Antiproliferative activity against human DU145 cells assessed as decrease in cell viability after 3 days by WST assay | Homo sapiens | 35 | ALA4190216 | cell-based format | Scientific Literature | |
| 3. | ALA4191525 | F | Antiproliferative activity against human LNCAP cells assessed as decrease in cell viability after 3 days by WST assay | Homo sapiens | 35 | ALA4190216 | cell-based format | Scientific Literature | |
| 4. | ALA4191526 | F | Potency index, ratio of curcumin IC50 to test compound IC50 for human PC3 cells | Homo sapiens | 34 | ALA4190216 | cell-based format | Scientific Literature | |
| 5. | ALA4191527 | F | Potency index, ratio of curcumin IC50 to test compound IC50 for human DU145 cells | Homo sapiens | 34 | ALA4190216 | cell-based format | Scientific Literature | |
| 6. | ALA4191528 | F | Potency index, ratio of curcumin IC50 to test compound IC50 for human LNCAP cells | Homo sapiens | 34 | ALA4190216 | cell-based format | Scientific Literature | |
| 7. | ALA4191529 | F | Antiproliferative activity against human PWR-1E cells expressing androgen receptor and PSA assessed as decrease in cell viability after 3 days by WST assay | Homo sapiens | 16 | ALA4190216 | cell-based format | Scientific Literature | |
| 8. | ALA4191530 | F | Potency index, ratio of curcumin IC50 to test compound IC50 for human PWR-1E cells expressing androgen receptor and PSA | Homo sapiens | 15 | ALA4190216 | cell-based format | Scientific Literature | |
| 9. | ALA4191531 | F | Antiproliferative activity against human LNCaP95 cells expressing androgen receptor splice variants assessed as decrease in cell viability after 5 days by trypan blue exclusion assay | Homo sapiens | 4 | ALA4190216 | cell-based format | Scientific Literature | |
| 10. | ALA4191532 | F | Antiproliferative activity against human VCaP cells expressing androgen receptor splice variants assessed as decrease in cell viability after 5 days by trypan blue exclusion assay | Homo sapiens | 4 | ALA4190216 | cell-based format | Scientific Literature | |
| 11. | ALA4191533 | F | Antiproliferative activity against human 22Rv1 cells expressing androgen receptor splice variants assessed as decrease in cell viability after 5 days by trypan blue exclusion assay | Homo sapiens | 4 | ALA4190216 | cell-based format | Scientific Literature | |
| 12. | ALA4191534 | A | Plasma concentration in Sprague-Dawley rat at 10 mg/kg administered via oral gavage measured at 1 hr by HPLC-MS/MS analysis | Rattus norvegicus | 4 | ALA4190216 | organism-based format | Scientific Literature | |
| 13. | ALA4191535 | A | Plasma concentration in Sprague-Dawley rat at 10 mg/kg administered via oral gavage measured at 3 hrs by HPLC-MS/MS analysis | Rattus norvegicus | 4 | ALA4190216 | organism-based format | Scientific Literature | |
| 14. | ALA4191536 | A | Plasma concentration in Sprague-Dawley rat at 10 mg/kg administered via oral gavage measured at 6 hrs by HPLC-MS/MS analysis | Rattus norvegicus | 4 | ALA4190216 | organism-based format | Scientific Literature | |
| 15. | ALA4191537 | A | Plasma concentration in Sprague-Dawley rat at 10 mg/kg administered via oral gavage measured after 1 day by HPLC-MS/MS analysis | Rattus norvegicus | 4 | ALA4190216 | organism-based format | Scientific Literature | |
| 16. | ALA4191538 | A | Tmax in Sprague-Dawley rat at 10 mg/kg administered via oral gavage by HPLC-MS/MS analysis | Rattus norvegicus | 4 | ALA4190216 | organism-based format | Scientific Literature | |
| 17. | ALA4191539 | A | Cmax in Sprague-Dawley rat at 10 mg/kg administered via oral gavage by HPLC-MS/MS analysis | Rattus norvegicus | 4 | ALA4190216 | organism-based format | Scientific Literature | |
| 18. | ALA4191540 | A | AUC in Sprague-Dawley rat at 10 mg/kg administered via oral gavage by HPLC-MS/MS analysis | Rattus norvegicus | 4 | ALA4190216 | organism-based format | Scientific Literature | |
| 19. | ALA4191541 | T | Acute toxicity in Sprague-Dawley rat at 10 mg/kg administered via oral gavage | Rattus norvegicus | 2 | ALA4190216 | organism-based format | Scientific Literature | |
| 20. | ALA4191544 | A | Drug metabolism in human liver microsomes assessed as (1E,4E)-1-(1-sec-butyl-4-hydroxy-1H-imidazol-2-yl)-5-(2-methyl-4-(trifluoromethyl)thiazol-5-yl)penta-1,4-dien-3-one formation at 10 mM after 60 mins by UHPLC analysis | Homo sapiens | 1 | ALA4190216 | microsome format | Scientific Literature |
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