#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4181719	Binding	Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by CaCl2 addition by Fluo-4-AM dye-based FLIPR assay	Homo sapiens	75	ALA4177680	cell-based format	Scientific Literature
2.	ALA4181720	Binding	Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by CaCl2 addition by Fluo-4-AM dye-based FLIPR assay	Homo sapiens	75	ALA4177680	cell-based format	Scientific Literature
3.	ALA4181721	Binding	Inhibition of recombinant Cav3.3 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by CaCl2 addition by Fluo-4-AM dye-based FLIPR assay	Homo sapiens	75	ALA4177680	cell-based format	Scientific Literature
4.	ALA4181725	Physicochemical	Solubility of the compound in phosphate buffer at pH 7 after 24 hrs by HPLC/UV method		32	ALA4177680	small-molecule physicochemical format	Scientific Literature
5.	ALA4181733	ADME	Total drug level in Wistar rat brain at 10 mg/kg administered via oral gavage measured after 1 hr by LC-MS/MS method	Rattus norvegicus	4	ALA4177680	organism-based format	Scientific Literature
6.	ALA4181734	ADME	Fraction unbound in Wistar rat brain at 10 mg/kg administered via oral gavage measured after 1 hr by rapid equilibrium dialysis method	Rattus norvegicus	14	ALA4177680	organism-based format	Scientific Literature
7.	ALA4181742	ADME	Drug level in Wistar rat cerebrospinal fluid at 10 mg/kg administered via oral gavage measured after 1 hr by LC-MS/MS method	Rattus norvegicus	4	ALA4177680	organism-based format	Scientific Literature
8.	ALA4181743	Physicochemical	Chemical stability of the compound in amorphous form at room temperature		2	ALA4177680	small-molecule physicochemical format	Scientific Literature
9.	ALA4181746	ADME	Half life in human plasma at 10 uM by LC-MS/MS method	Homo sapiens	1	ALA4177680	cell-free format	Scientific Literature
10.	ALA4181747	ADME	Half life in rat plasma at 10 uM by LC-MS/MS method	Rattus norvegicus	1	ALA4177680	cell-free format	Scientific Literature
11.	ALA4181748	ADME	Drug metabolism in human plasma assessed as 3-amino-1-(3,4-difluorobenzyl)pyrazole formation at 10 uM by LC-MS/MS method	Homo sapiens	1	ALA4177680	cell-free format	Scientific Literature
12.	ALA4181749	ADME	Drug metabolism in rat plasma assessed as 3-amino-1-(3,4-difluorobenzyl)pyrazole formation at 10 uM by LC-MS/MS method	Rattus norvegicus	1	ALA4177680	cell-free format	Scientific Literature