# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4181719 | Binding | Inhibition of recombinant Cav3.1 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by CaCl2 addition by Fluo-4-AM dye-based FLIPR assay | Homo sapiens | 75 | ALA4177680 | cell-based format | Scientific Literature | |
2. | ALA4181720 | Binding | Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by CaCl2 addition by Fluo-4-AM dye-based FLIPR assay | Homo sapiens | 75 | ALA4177680 | cell-based format | Scientific Literature | |
3. | ALA4181721 | Binding | Inhibition of recombinant Cav3.3 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by CaCl2 addition by Fluo-4-AM dye-based FLIPR assay | Homo sapiens | 75 | ALA4177680 | cell-based format | Scientific Literature | |
4. | ALA4181722 | Binding | Inhibition of recombinant Cav1.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by KCl addition by Fluo-4-AM dye-based FLIPR assay | Homo sapiens | 8 | ALA4177680 | cell-based format | Scientific Literature | |
5. | ALA4181725 | Physicochemical | Solubility of the compound in phosphate buffer at pH 7 after 24 hrs by HPLC/UV method | 32 | ALA4177680 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA4181726 | Physicochemical | Solubility of the compound in FeSSIF | 4 | ALA4177680 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA4181727 | Physicochemical | Solubility of the compound in FaSSIF | 4 | ALA4177680 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA4181734 | ADME | Fraction unbound in Wistar rat brain at 10 mg/kg administered via oral gavage measured after 1 hr by rapid equilibrium dialysis method | Rattus norvegicus | 14 | ALA4177680 | organism-based format | Scientific Literature |