# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4193271 | Functional | Cytotoxicity against human A549/DXR cells assessed as reduction in cell viability after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay | Homo sapiens | 3 | ALA4190305 | cell-based format | Scientific Literature | |
2. | ALA4193272 | ADME | Cytotoxicity against human MDA-MB-231 cells harboring p53 R280K mutant assessed as reduction in cell viability after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay | Homo sapiens | 3 | ALA4190305 | cell-based format | Scientific Literature | |
3. | ALA4193273 | ADME | Cytotoxicity against p53 null human HCT116 cells assessed as reduction in cell viability after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay | Homo sapiens | 3 | ALA4190305 | cell-based format | Scientific Literature | |
4. | ALA4193274 | ADME | Cytotoxicity against human HCT116 cells harboring wild type p53 assessed as reduction in cell viability after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay | Homo sapiens | 3 | ALA4190305 | cell-based format | Scientific Literature | |
5. | ALA4193275 | ADME | Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay | Homo sapiens | 3 | ALA4190305 | cell-based format | Scientific Literature | |
6. | ALA4193276 | ADME | Cytotoxicity against human U2OS cells assessed as reduction in cell viability after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay | Homo sapiens | 3 | ALA4190305 | cell-based format | Scientific Literature | |
7. | ALA4193277 | Binding | Inhibition of Pgp in human A549/DXR cells assessed as increase in calcein-AM efflux after 1 hr by fluorescence assay | Homo sapiens | 3 | ALA4190305 | cell-based format | Scientific Literature | |
8. | ALA4193278 | Functional | Inhibition of calcein-AM efflux in human A549 cells at 10 uM after 1 hr by fluorescence assay | Homo sapiens | 3 | ALA4190305 | cell-based format | Scientific Literature | |
9. | ALA4193279 | ADME | Cytotoxicity against p53 CRISPR-Cas9 knockout human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay | Homo sapiens | 3 | ALA4190305 | cell-based format | Scientific Literature | |
10. | ALA4193280 | Functional | Inhibition of calcein-AM efflux in p53 CRISPR-Cas9 knockout human MDA-MB-231 cells after 1 hr by fluorescence assay | Homo sapiens | 3 | ALA4190305 | cell-based format | Scientific Literature | |
11. | ALA4193281 | Functional | Potentiation of doxorubicin-induced cytotoxicity against human A549 cells assessed as decrease in cell viability at 10 uM after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay | Homo sapiens | 3 | ALA4190305 | cell-based format | Scientific Literature | |
12. | ALA4193282 | Functional | Potentiation of doxorubicin-induced cytotoxicity against human U2OS cells assessed as decrease in cell viability at 10 uM after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay | Homo sapiens | 3 | ALA4190305 | cell-based format | Scientific Literature | |
13. | ALA4193283 | Functional | Potentiation of doxorubicin-induced cytotoxicity against p53 CRISPR-Cas9 knockout human MDA-MB-231 cells assessed as decrease in cell viability at 10 uM after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay | Homo sapiens | 3 | ALA4190305 | cell-based format | Scientific Literature | |
14. | ALA4193284 | Functional | Potentiation of doxorubicin-induced cytotoxicity against p53 null human Saos2 cells assessed as decrease in cell viability at 10 uM after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay | Homo sapiens | 3 | ALA4190305 | cell-based format | Scientific Literature |