| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4182207 | B | Inhibition of HCV genotype 1b Con1 NS3 protease infected in human HuH7 replicon cells assessed as reduction in viral replication after 4 days by luciferase reporter gene assay | Hepatitis C virus (isolate Con1) | 22 | cell-based format | Scientific Literature | ||
| 2. | ALA4182208 | B | Inhibition of HCV genotype 1a H77 NS3 protease infected in human HuH7 replicon cells assessed as reduction in viral replication after 4 days by luciferase reporter gene assay | Hepatitis C virus (isolate H77) | 21 | cell-based format | Scientific Literature | ||
| 3. | ALA4182212 | A | Half life in human liver microsomes in presence of NADPH | Homo sapiens | 12 | microsome format | Scientific Literature | ||
| 4. | ALA4182214 | A | Clearance in Sprague-Dawley rat at 5 mg/kg, iv after 24 hrs | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 5. | ALA4182215 | A | Half life in Sprague-Dawley rat at 5 mg/kg, iv after 24 hrs | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 6. | ALA4182216 | A | AUC in Sprague-Dawley rat at 5 mg/kg, iv after 24 hrs | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 7. | ALA4182218 | A | Oral bioavailability in Sprague-Dawley rat at 15 mg/kg after 24 hrs | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 8. | ALA4182237 | A | Half life in Sprague-Dawley rat at 15 mg/kg, po after 24 hrs | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 9. | ALA4182238 | A | AUC in Sprague-Dawley rat at 15 mg/kg, po after 24 hrs | Rattus norvegicus | 4 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!