# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4188458 | F | Effect on hypoxanthine/xanthine oxidase-induced superoxide radical scavenging activity up to 100 uM incubated for 1 min measured for 15 mins by cytochrome C assay | 3 | ALA4184268 | assay format | Scientific Literature | ||
2. | ALA4188459 | F | Effect on hydrogen peroxide radical scavenging activity up to 100 uM measured after 5 mins by Amplex Red assay | 3 | ALA4184268 | assay format | Scientific Literature | ||
3. | ALA4188460 | B | Inhibition of Nox4 in HASMCs assessed as reduction in TGFbeta-induced increase in smooth muscle alpha actin level pretreated for 30 mins followed by TGFbeta stimulation after 24 hrs by Western blot analysis | Homo sapiens | 3 | ALA4184268 | single protein format | Scientific Literature | |
4. | ALA4188461 | F | Effect on TGFbeta-induced Nox4 mRNA expression in HASMCs at 1 to 100 uM pretreated for 30 mins followed by TGFbeta addition measured after 24 hrs by qPCR analysis | Homo sapiens | 3 | ALA4184268 | cell-based format | Scientific Literature | |
5. | ALA4188463 | A | Cytotoxicity against HASMCs assessed as cell viability at 10 uM after 24 hrs by calcein/AM/ethidium homodimer-1 staining based fluorescence microscopic analysis relative to control | Homo sapiens | 1 | ALA4184268 | cell-based format | Scientific Literature |