# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4188520 | ADME | Inhibition of recombinant human full length CDK1/Cyclin D3 expressed in baculovirus infected Sf9 insect cells using histone H1 substrate after 90 mins by ADP-Glo assay | Homo sapiens | 24 | ALA4184274 | cell-based format | Scientific Literature | |
2. | ALA4188521 | Binding | Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assay | Homo sapiens | 24 | ALA4184274 | single protein format | Scientific Literature | |
3. | ALA4188522 | Binding | Inhibition of recombinant human full length CDK6 expressed in baculovirus infected Sf9 insect cells using histone H1 substrate after 90 mins by ADP-Glo assay | Homo sapiens | 24 | ALA4184274 | cell-based format | Scientific Literature | |
4. | ALA4188523 | Functional | Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by DAPI staining based assay | Homo sapiens | 8 | ALA4184274 | cell-based format | Scientific Literature | |
5. | ALA4188524 | Binding | Inhibition of human ERG | Homo sapiens | 3 | ALA4184274 | single protein format | Scientific Literature | |
6. | ALA4188525 | ADME | Cmax in rat at 5 mg/kg | Rattus norvegicus | 2 | ALA4184274 | organism-based format | Scientific Literature | |
7. | ALA4188526 | ADME | AUC in rat at 5 mg/kg | Rattus norvegicus | 2 | ALA4184274 | organism-based format | Scientific Literature | |
8. | ALA4188527 | ADME | Half life in rat at 5 mg/kg | Rattus norvegicus | 2 | ALA4184274 | organism-based format | Scientific Literature | |
9. | ALA4188528 | ADME | MRT in rat at 5 mg/kg | Rattus norvegicus | 2 | ALA4184274 | organism-based format | Scientific Literature | |
10. | ALA4188529 | ADME | Apparent clearance in rat at 5 mg/kg | Rattus norvegicus | 2 | ALA4184274 | organism-based format | Scientific Literature | |
11. | ALA4188530 | ADME | Apparent volume of distribution in rat at 5 mg/kg | Rattus norvegicus | 2 | ALA4184274 | organism-based format | Scientific Literature |