# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4188758 | Functional | Agonist activity at recombinant human GPR120 short isoform expressed in HEK293 cells assessed as intracellular calcium flux measured for 300 secs at 1 sec time interval by Fluo-4 NW based FLIPR assay | Homo sapiens | 34 | ALA4184291 | cell-based format | Scientific Literature | |
2. | ALA4188759 | ADME | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 3 | ALA4184291 | single protein format | Scientific Literature | |
3. | ALA4188760 | ADME | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 3 | ALA4184291 | single protein format | Scientific Literature | |
4. | ALA4188761 | ADME | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 3 | ALA4184291 | single protein format | Scientific Literature | |
5. | ALA4188762 | ADME | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 3 | ALA4184291 | single protein format | Scientific Literature | |
6. | ALA4188763 | ADME | Inhibition of CYP2C19 (unknown origin) | Homo sapiens | 3 | ALA4184291 | single protein format | Scientific Literature | |
7. | ALA4188764 | ADME | Half life in human liver microsomes | Homo sapiens | 3 | ALA4184291 | microsome format | Scientific Literature | |
8. | ALA4188765 | ADME | Half life in mouse liver microsomes | Mus musculus | 3 | ALA4184291 | microsome format | Scientific Literature | |
9. | ALA4188766 | ADME | Half life in rat liver microsomes | Rattus norvegicus | 3 | ALA4184291 | microsome format | Scientific Literature | |
10. | ALA4188767 | ADME | Protein binding in human plasma | Homo sapiens | 3 | ALA4184291 | cell-free format | Scientific Literature | |
11. | ALA4188768 | ADME | Protein binding in mouse plasma | Mus musculus | 3 | ALA4184291 | cell-free format | Scientific Literature | |
12. | ALA4188769 | ADME | Protein binding in rat plasma | Rattus norvegicus | 3 | ALA4184291 | cell-free format | Scientific Literature | |
13. | ALA4188770 | ADME | Half life in mouse at 1.15 mg/kg, iv by LC-MS/MS analysis | Mus musculus | 1 | ALA4184291 | organism-based format | Scientific Literature | |
14. | ALA4188771 | ADME | Clearance in mouse at 1.15 mg/kg, iv by LC-MS/MS analysis | Mus musculus | 1 | ALA4184291 | organism-based format | Scientific Literature | |
15. | ALA4188772 | ADME | Volume of distribution at steady state in mouse at 1.15 mg/kg, iv by LC-MS/MS analysis | Mus musculus | 1 | ALA4184291 | organism-based format | Scientific Literature | |
16. | ALA4188773 | ADME | Half life in mouse at 14.6 mg/kg, po by LC-MS/MS analysis | Mus musculus | 1 | ALA4184291 | organism-based format | Scientific Literature | |
17. | ALA4188774 | ADME | Cmax in mouse at 14.6 mg/kg, po by LC-MS/MS analysis | Mus musculus | 1 | ALA4184291 | organism-based format | Scientific Literature | |
18. | ALA4188775 | ADME | AUClast in mouse at 14.6 mg/kg, po by LC-MS/MS analysis | Mus musculus | 1 | ALA4184291 | organism-based format | Scientific Literature | |
19. | ALA4188776 | ADME | Oral bioavailability in mouse at 14.6 mg/kg by LC-MS/MS analysis | Mus musculus | 1 | ALA4184291 | organism-based format | Scientific Literature | |
20. | ALA4188777 | ADME | Half life in rat at 2 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 1 | ALA4184291 | organism-based format | Scientific Literature |