# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4188758 | F | Agonist activity at recombinant human GPR120 short isoform expressed in HEK293 cells assessed as intracellular calcium flux measured for 300 secs at 1 sec time interval by Fluo-4 NW based FLIPR assay | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
2. | ALA4188759 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
3. | ALA4188760 | A | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
4. | ALA4188761 | A | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
5. | ALA4188762 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
6. | ALA4188763 | A | Inhibition of CYP2C19 (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
7. | ALA4188764 | A | Half life in human liver microsomes | Homo sapiens | 3 | microsome format | Scientific Literature | ||
8. | ALA4188765 | A | Half life in mouse liver microsomes | Mus musculus | 3 | microsome format | Scientific Literature | ||
9. | ALA4188766 | A | Half life in rat liver microsomes | Rattus norvegicus | 3 | microsome format | Scientific Literature | ||
10. | ALA4188767 | A | Protein binding in human plasma | Homo sapiens | 3 | cell-free format | Scientific Literature | ||
11. | ALA4188768 | A | Protein binding in mouse plasma | Mus musculus | 3 | cell-free format | Scientific Literature | ||
12. | ALA4188769 | A | Protein binding in rat plasma | Rattus norvegicus | 3 | cell-free format | Scientific Literature | ||
13. | ALA4188770 | A | Half life in mouse at 1.15 mg/kg, iv by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
14. | ALA4188771 | A | Clearance in mouse at 1.15 mg/kg, iv by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
15. | ALA4188772 | A | Volume of distribution at steady state in mouse at 1.15 mg/kg, iv by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
16. | ALA4188773 | A | Half life in mouse at 14.6 mg/kg, po by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
17. | ALA4188774 | A | Cmax in mouse at 14.6 mg/kg, po by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
18. | ALA4188775 | A | AUClast in mouse at 14.6 mg/kg, po by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
19. | ALA4188776 | A | Oral bioavailability in mouse at 14.6 mg/kg by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
20. | ALA4188777 | A | Half life in rat at 2 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature |