| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4182524 | B | Inhibition of recombinant human MAO-B using benzylamine as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by amplex red reagent based spectrophotometric assay | Homo sapiens | 48 | ALA4177719 | single protein format | Scientific Literature | |
| 2. | ALA4182525 | B | Inhibition of recombinant human MAO-A using p-tyramine as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by amplex red reagent based spectrophotometric assay | Homo sapiens | 47 | ALA4177719 | single protein format | Scientific Literature | |
| 3. | ALA4182526 | B | Selectivity index, ratio of IC50 for recombinant human MAO-A to IC50 for recombinant human MAO-B | Homo sapiens | 48 | ALA4177719 | assay format | Scientific Literature | |
| 4. | ALA4272739 | B | Inhibition of C-terminal His-tagged human ARTD10 (809 to 1017 residues) expressed in Escherichia coli Rosetta2 (DE3) using SRPK2 as substrate after 13 hrs in presence of NAD+ | Homo sapiens | 25 | ALA4270552 | assay format | Scientific Literature | |
| 5. | ALA4272742 | B | Inhibition of N-terminal His-tagged human ARTD1 (1 to 1014 residues) expressed in Escherichia coli Rosetta2 (DE3) using activated DNA as substrate after 1.5 hrs in presence of NAD+ | Homo sapiens | 5 | ALA4270552 | assay format | Scientific Literature | |
| 6. | ALA4272743 | B | Inhibition of N-terminal His-tagged thioredoxin-fused human ARTD2 (1 to 583 residues) expressed in Escherichia coli Rosetta2 (DE3) using activated DNA as substrate after 1.5 hrs in presence of NAD+ | Homo sapiens | 5 | ALA4270552 | assay format | Scientific Literature | |
| 7. | ALA4272744 | B | Inhibition of N-terminal His-tagged thioredoxin-fused human ARTD3 (1 to 533 residues) expressed in Escherichia coli Rosetta2 (DE3) using DNA as substrate after 3 hrs in presence of NAD+ | Homo sapiens | 5 | ALA4270552 | assay format | Scientific Literature | |
| 8. | ALA4272745 | B | Inhibition of N-terminal His-tagged human ARTD4 (250 to 565 residues) expressed in Escherichia coli Rosetta2 (DE3) using TCEP as substrate after 2.5 hrs in presence of NAD+ | Homo sapiens | 5 | ALA4270552 | assay format | Scientific Literature | |
| 9. | ALA4272746 | B | Inhibition of N-terminal His-tagged human ARTD5 (1030 to 1317 residues) expressed in Escherichia coli Rosetta2 (DE3) using TCEP as substrate after 18 hrs in presence of NAD+ | Homo sapiens | 5 | ALA4270552 | assay format | Scientific Literature | |
| 10. | ALA4272747 | B | Inhibition of N-terminal His-tagged Z-basic-fused human ARTD6 (873 to 1161 residues) expressed in Escherichia coli Rosetta2 (DE3) using TCEP as substrate after 18 hrs in presence of NAD+ | Homo sapiens | 5 | ALA4270552 | assay format | Scientific Literature | |
| 11. | ALA4272748 | B | Inhibition of N-terminal His-tagged human ARTD7 (482 to 678 residues) expressed in Escherichia coli Rosetta2 (DE3) using SRPK2 as substrate after 3 hrs in presence of NAD+ | Homo sapiens | 5 | ALA4270552 | assay format | Scientific Literature | |
| 12. | ALA4272749 | B | Inhibition of N-terminal His-tagged thioredoxin-fused human ARTD8 (1535 to 1801 residues) expressed in Escherichia coli Rosetta2 (DE3) after 21 hrs in presence of NAD+ | Homo sapiens | 5 | ALA4270552 | assay format | Scientific Literature | |
| 13. | ALA4272750 | B | Inhibition of N-terminal His-tagged thioredoxin-fused human ARTD12 (469 to 701 residues) expressed in Escherichia coli Rosetta2 (DE3) after 20 hrs in presence of NAD+ | Homo sapiens | 5 | ALA4270552 | assay format | Scientific Literature | |
| 14. | ALA4272751 | B | Inhibition of N-terminal His-tagged human ARTD15 (1 to 280 residues) expressed in Escherichia coli Rosetta2 (DE3) after 24 hrs in presence of NAD+ | Homo sapiens | 5 | ALA4270552 | assay format | Scientific Literature | |
| 15. | ALA4272752 | B | Stabilization of C-terminal His-tagged human ARTD10 (809 to 1017 residues) expressed in Escherichia coli Rosetta2 (DE3) assessed as change in melting temperature at 100 uM by SYPRO Orange-dye based differential scanning fluorimetric method | Homo sapiens | 5 | ALA4270552 | assay format | Scientific Literature | |
| 16. | ALA4272753 | B | Stabilization of ARTD10 in human U2OS cells assessed as increase in melting temperature at 10 uM by CESTA | Homo sapiens | 3 | ALA4270552 | cell-based format | Scientific Literature | |
| 17. | ALA4272754 | B | Stabilization of human ARTD9 expressed in Escherichia coli assessed as change in melting temperature at 100 uM by SYPRO Orange-dye based differential scanning fluorimetric method | Homo sapiens | 5 | ALA4270552 | assay format | Scientific Literature | |
| 18. | ALA4272755 | B | Stabilization of human ARTD13 expressed in Escherichia coli assessed as change in melting temperature at 100 uM by SYPRO Orange-dye based differential scanning fluorimetric method | Homo sapiens | 5 | ALA4270552 | assay format | Scientific Literature | |
| 19. | ALA4272756 | B | Inhibition of ARTD10 (unknown origin)-induced cell death expressed in human HeLa cells after 10 days by methylene blue staining based colony formation assay | Homo sapiens | 4 | ALA4270552 | cell-based format | Scientific Literature | |
| 20. | ALA4272757 | B | Inhibition of ARTD10 (unknown origin) G888W mutant-induced cell death expressed in human HeLa cells at 5 uM after 10 days by methylene blue staining based colony formation assay | Homo sapiens | 2 | ALA4270552 | cell-based format | Scientific Literature |
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