| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4178741 | Functional | Antagonist activity at human GPR4 expressed in human HeLa cells assessed as inhibition of IBMX-induced cAMP accumulation after 15 mins by HTRF assay | Homo sapiens | 13 | ALA4177561 | cell-based format | Scientific Literature | |
| 2. | ALA4178742 | Binding | Displacement of [3H]dofetilide from recombinant human ERG expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting method | Homo sapiens | 13 | ALA4177561 | cell-based format | Scientific Literature | |
| 3. | ALA4178743 | Binding | Selectivity ratio of IC50 for displacement of [3H]dofetilide from recombinant human ERG expressed in HEK293 cell membranes to IC50 for human GPR4 expressed in HeLa cells | Homo sapiens | 13 | ALA4177561 | cell-based format | Scientific Literature | |
| 4. | ALA4178744 | Binding | Displacement of [3H]-R(-)-alpha-Methyl[imidazole-2.5(n)]histamine from human recombinant histamine H3 receptor expressed in CHOK1 cell membranes after 1 hr by scintillation counting method | Homo sapiens | 13 | ALA4177561 | cell-based format | Scientific Literature | |
| 5. | ALA4178745 | ADME | Clearance in Sprague-Dawley rat at 1 mg/kg, iv | Rattus norvegicus | 11 | ALA4177561 | organism-based format | Scientific Literature | |
| 6. | ALA4178746 | ADME | Dose normalized AUC in Sprague-Dawley rat at 3 mg/kg, po | Rattus norvegicus | 11 | ALA4177561 | organism-based format | Scientific Literature |
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