| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4184872 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 2. | ALA4184873 | P | Aqueous solubility of the compound at pH 6.8 | 14 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA4184874 | A | Half life in nude mouse at 1 mg/kg, iv by HPLC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA4184875 | A | Clearance in nude mouse at 1 mg/kg, iv by HPLC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA4184876 | F | Antiproliferative activity against human A2780 cells after 4 days by CellTiter-Glo assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
| 6. | ALA4184877 | F | Antiproliferative activity against human COR-L23 cells after 4 days by CellTiter-Glo assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
| 7. | ALA4184879 | F | Antitumor activity against human COR-L23 cells xenografted in nude mouse assessed as reduction in tumor growth at 10 mg/kg, po bid administered for 3 days starting from day 7 post implantation measured every 2 to 3 days for 18 days | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA4184881 | A | Volume of distribution at steady state in nude mouse at 1 mg/kg, iv by HPLC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA4184882 | A | Cmax in nude mouse at 10 mg/kg, po by HPLC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA4184883 | A | Tmax in nude mouse at 10 mg/kg, po by HPLC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA4184884 | A | Oral bioavailability in nude mouse at 10 mg/kg by HPLC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA4184885 | A | AUC in nude mouse at 1 mg/kg, iv by HPLC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA4184886 | A | AUC in nude mouse at 10 mg/kg, po by HPLC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA4184891 | A | Permeability of the compound by PAMPA | 11 | assay format | Scientific Literature | |||
| 15. | ALA4184893 | F | Increase in fructose-6-phosphate level in tumor of nude mouse xenografted with human COR-L23 cells at 5 to 10 mg/kg, po bid measured up to 72 hrs by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA4184894 | F | Increase in glucose-6-phosphate level in tumor of nude mouse xenografted with human COR-L23 cells at 5 to 10 mg/kg, po bid measured up to 72 hrs by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA4184895 | A | Clearance in mouse liver microsomes | Mus musculus | 9 | microsome format | Scientific Literature |
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