| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4186119 | Binding | Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assay | Homo sapiens | 38 | ALA4184149 | cell-based format | Scientific Literature | |
| 2. | ALA4186121 | Physicochemical | Solubility of the compound in propylene glycol/ethanol96 at 30 mg/ml after 24 hrs by UV-spectrometric analysis | 38 | ALA4184149 | small-molecule physicochemical format | Scientific Literature | ||
| 3. | ALA4186123 | ADME | Intrinsic clearance in human hepatocytes assessed per million cells at 1 uM by LC-MS/MS analysis | Homo sapiens | 12 | ALA4184149 | cell-based format | Scientific Literature | |
| 4. | ALA4186126 | Toxicity | Genotoxicity in p53-competent human TK6 cells in presence of Sprague-Dawley rat S9 fraction by GADD45alpha GFP reporter assay | Homo sapiens | 15 | ALA4184149 | cell-based format | Scientific Literature | |
| 5. | ALA4186127 | Toxicity | Genotoxicity in p53-competent human TK6 cells in absence of Sprague-Dawley rat S9 fraction by GADD45alpha GFP reporter assay | Homo sapiens | 15 | ALA4184149 | cell-based format | Scientific Literature |
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