| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4189777 | Binding | Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence polarization assay | Homo sapiens | 29 | ALA4184328 | cell-based format | Scientific Literature | |
| 2. | ALA4189778 | Binding | Binding affinity to menin in mouse bone marrow cells harboring MLL-AF9 fusion protein assessed as inhibition of protein interaction with MLL by measuring cell growth inhibition after 7 days by MTT assay | Mus musculus | 29 | ALA4184328 | cell-based format | Scientific Literature | |
| 3. | ALA4189779 | ADME | Half life in CD-1 mouse liver microsomes at 1 uM after 3 to 60 mins by LC-MS/MS method | Mus musculus | 29 | ALA4184328 | microsome format | Scientific Literature |
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