# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4187003 | B | Transactivation of mouse Gal4-fused RARalpha-LBD expressed in COS-7 cells after 1 day by bright-Glo reagent based assay relative to control ATRA | Mus musculus | 41 | ALA4184197 | cell-based format | Scientific Literature | |
2. | ALA4187005 | B | Transactivation of mouse Gal4-fused RARbeta-LBD expressed in COS-7 cells after 1 day by bright-Glo reagent based assay relative to control ATRA | Mus musculus | 23 | ALA4184197 | cell-based format | Scientific Literature | |
3. | ALA4187007 | B | Ratio of relative EC50 for mouse Gal4-fused RARbeta-LBD expressed in COS-7 cells to relative EC50 for mouse Gal4-fused RARalpha-LBD expressed in COS-7 cells | Mus musculus | 40 | ALA4184197 | cell-based format | Scientific Literature | |
4. | ALA4187008 | B | Transactivation of mouse Gal4-fused RARgamma-LBD expressed in COS-7 cells after 1 day by bright-Glo reagent based assay relative to control ATRA | Mus musculus | 23 | ALA4184197 | cell-based format | Scientific Literature | |
5. | ALA4187010 | B | Ratio of relative EC50 for mouse Gal4-fused RARgamma-LBD expressed in COS-7 cells to relative EC50 for mouse Gal4-fused RARalpha-LBD expressed in COS-7 cells | Mus musculus | 40 | ALA4184197 | cell-based format | Scientific Literature | |
6. | ALA4187011 | P | Octanol/buffer partition co-efficient, log D of the compound at pH 7.4 by LC-MS/MS based shake-flask method | 17 | ALA4184197 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA4187012 | A | Intrinsic clearance in mouse liver microsomes assessed per mg protein in presence of NADPH by LC-MS/MS analysis | Mus musculus | 18 | ALA4184197 | microsome format | Scientific Literature | |
8. | ALA4187013 | A | Intrinsic clearance in human liver microsomes assessed per mg protein in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 16 | ALA4184197 | microsome format | Scientific Literature |