# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4202003 | P | Thermodynamic solubility of the compound by quantitative nitrogen detection assay | 10 | ALA4196215 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA4202007 | B | Inhibition of human recombinant ALDH1A1 assessed as reduction in of NAD(P)H formation incubated for 2 mins by spectrophotometry | Homo sapiens | 28 | ALA4196215 | single protein format | Scientific Literature | |
3. | ALA4202008 | B | Inhibition of human recombinant ALDH1A2 assessed as reduction in of NAD(P)H formation incubated for 2 mins by spectrophotometry | Homo sapiens | 22 | ALA4196215 | single protein format | Scientific Literature | |
4. | ALA4202010 | B | Inhibition of human recombinant ALDH1A3 assessed as reduction in of NAD(P)H formation incubated for 2 mins by spectrophotometry | Homo sapiens | 22 | ALA4196215 | single protein format | Scientific Literature | |
5. | ALA4202012 | B | Inhibition of human recombinant ALDH2 assessed as enzyme activity by measuring NAD(P)H formation at 20 uM incubated for 2 mins by spectrophotometry | Homo sapiens | 31 | ALA4196215 | single protein format | Scientific Literature | |
6. | ALA4202021 | B | Inhibition of ALDH1A3 in human PEO1 cells assessed as reduction in aldefluor positive cells at 30 uM incubated for 30 mins by aldefluor assay | Homo sapiens | 1 | ALA4196215 | cell-based format | Scientific Literature | |
7. | ALA4202022 | B | Inhibition of ALDH1A3 in human OVCAR5 cells assessed as reduction in aldefluor positive cells at 30 uM incubated for 30 mins by aldefluor assay | Homo sapiens | 1 | ALA4196215 | cell-based format | Scientific Literature | |
8. | ALA4202023 | B | Inhibition of ALDH1A3 in human PEO1 cells assessed as reduction in CD133 protein expression incubated for 48 hrs by CD133/2-APC antibody based assay | Homo sapiens | 5 | ALA4196215 | cell-based format | Scientific Literature | |
9. | ALA4202024 | B | Inhibition of ALDH1A3 in human OVCAR5 cells assessed as reduction in CD133 protein expression incubated for 48 hrs by CD133/2-APC antibody based assay | Homo sapiens | 5 | ALA4196215 | cell-based format | Scientific Literature | |
10. | ALA4202029 | F | Potentiation of 6 uM cisplatin-induced cytotoxicity in human PEO1 cells assessed as combination index at 1 uM incubated for 72 hrs by cell-titer Glo assay based Chou-Talalay method | Homo sapiens | 4 | ALA4196215 | cell-based format | Scientific Literature | |
11. | ALA4202030 | F | Potentiation of 3 uM cisplatin-induced cytotoxicity in human PEO1 cells assessed as combination index at 1 uM incubated for 72 hrs by cell-titer Glo assay based Chou-Talalay method | Homo sapiens | 4 | ALA4196215 | cell-based format | Scientific Literature | |
12. | ALA4202031 | F | Potentiation of 1.5 uM cisplatin-induced cytotoxicity in human PEO1 cells assessed as combination index at 1 uM incubated for 72 hrs by cell-titer Glo assay based Chou-Talalay method | Homo sapiens | 4 | ALA4196215 | cell-based format | Scientific Literature | |
13. | ALA4202032 | F | Potentiation of 0.75 uM cisplatin-induced cytotoxicity in human PEO1 cells assessed as combination index at 1 uM incubated for 72 hrs by cell-titer Glo assay based Chou-Talalay method | Homo sapiens | 4 | ALA4196215 | cell-based format | Scientific Literature | |
14. | ALA4202033 | F | Potentiation of 6 uM cisplatin-induced cytotoxicity in human PEO1 cells assessed as combination index at 10 uM incubated for 72 hrs by cell-titer Glo assay based Chou-Talalay method | Homo sapiens | 4 | ALA4196215 | cell-based format | Scientific Literature | |
15. | ALA4202034 | F | Potentiation of 3 uM cisplatin-induced cytotoxicity in human PEO1 cells assessed as combination index at 10 uM incubated for 72 hrs by cell-titer Glo assay based Chou-Talalay method | Homo sapiens | 4 | ALA4196215 | cell-based format | Scientific Literature | |
16. | ALA4202035 | F | Potentiation of 1.5 uM cisplatin-induced cytotoxicity in human PEO1 cells assessed as combination index at 10 uM incubated for 72 hrs by cell-titer Glo assay based Chou-Talalay method | Homo sapiens | 4 | ALA4196215 | cell-based format | Scientific Literature | |
17. | ALA4202036 | F | Potentiation of 0.75 uM cisplatin-induced cytotoxicity in human PEO1 cells assessed as combination index at 10 uM incubated for 72 hrs by cell-titer Glo assay based Chou-Talalay method | Homo sapiens | 4 | ALA4196215 | cell-based format | Scientific Literature | |
18. | ALA4202037 | F | Potentiation of 6 uM cisplatin-induced cytotoxicity in human OVCAR5 cells assessed as combination index at 1 uM incubated for 72 hrs by cell-titer Glo assay based Chou-Talalay method | Homo sapiens | 4 | ALA4196215 | cell-based format | Scientific Literature | |
19. | ALA4202038 | F | Potentiation of 3 uM cisplatin-induced cytotoxicity in human OVCAR5 cells assessed as combination index at 1 uM incubated for 72 hrs by cell-titer Glo assay based Chou-Talalay method | Homo sapiens | 4 | ALA4196215 | cell-based format | Scientific Literature | |
20. | ALA4202039 | F | Potentiation of 1.5 uM cisplatin-induced cytotoxicity in human OVCAR5 cells assessed as combination index at 1 uM incubated for 72 hrs by cell-titer Glo assay based Chou-Talalay method | Homo sapiens | 4 | ALA4196215 | cell-based format | Scientific Literature |