# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4188356 | B | Estrogenic activity at ERalpha/ERbeta (unknown origin) expressed in human HepG2 cells co-expressing ERE-dependent promoter assessed as increase in ER-mediated transcriptional activation at 1 uM incubated for 24 hrs by luciferase reporter gene assay relative to untreated control | Homo sapiens | 28 | ALA4184258 | cell-based format | Scientific Literature | |
2. | ALA4188357 | B | Estrogenic activity at ERalpha/ERbeta (unknown origin) expressed in human HepG2 cells co-expressing ERE-dependent promoter assessed as increase in ER-mediated transcriptional activation at 10 uM incubated for 24 hrs by luciferase reporter gene assay relative to untreated control | Homo sapiens | 28 | ALA4184258 | cell-based format | Scientific Literature | |
3. | ALA4604333 | B | Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectrophotometric method | Homo sapiens | 21 | ALA4602658 | single protein format | Scientific Literature | |
4. | ALA4604334 | B | Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate by Dixon plot analysis | Homo sapiens | 21 | ALA4602658 | single protein format | Scientific Literature | |
5. | ALA4604335 | B | Noncompetitive inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate by Lineweaver-Burk plot analysis | Homo sapiens | 21 | ALA4602658 | single protein format | Scientific Literature |