| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4199509 | B | Inhibition of sPLA2-10 (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate pretreated for 20 mins followed by substrate addition and measured after 60 mins by NEFA based assay | Homo sapiens | 18 | single protein format | Scientific Literature | ||
| 2. | ALA4199510 | B | Inhibition of sPLA2-2A (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate pretreated for 20 mins followed by substrate addition and measured after 60 mins by NEFA based assay | Homo sapiens | 16 | single protein format | Scientific Literature | ||
| 3. | ALA4199511 | B | Inhibition of sPLA2-5 (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate pretreated for 20 mins followed by substrate addition and measured after 60 mins by NEFA based assay | Homo sapiens | 15 | single protein format | Scientific Literature | ||
| 4. | ALA4199514 | B | Inhibition of recombinant human sPLA2-10 using human HDL as substrate pretreated for 20 mins followed by substrate addition and measured after 60 mins by NEFA based assay | Homo sapiens | 17 | single protein format | Scientific Literature | ||
| 5. | ALA4199516 | P | Lipophilicity, log D of compound at pH 7.4 | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA4199517 | B | Selectivity ratio of IC50 for sPLA2-2A (unknown origin) to IC50 for sPLA2-10 (unknown origin) | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 7. | ALA4199518 | B | Selectivity ratio of IC50 for sPLA2-5 (unknown origin) to IC50 for sPLA2-10 (unknown origin) | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 8. | ALA4199519 | A | Unbound clearance in C57Bl/6J mouse administered iv or po | Mus musculus | 12 | organism-based format | Scientific Literature |
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