# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4198422 | Binding | Binding affinity to Keap1 in human HaCaT cells assessed as induction of NRF2/ARE activation-mediated HO1 expression at 10 uM after 6 to 24 hrs by Western blot analysis | Homo sapiens | 16 | ALA4196072 | cell-based format | Scientific Literature | |
2. | ALA4198423 | Binding | Binding affinity to Keap1 in human HaCaT cells assessed as induction of NRF2/ARE activation-mediated HO1 mRNA expression at 10 uM RT-PCR method | Homo sapiens | 4 | ALA4196072 | cell-based format | Scientific Literature | |
3. | ALA4198424 | ADME | Cytotoxicity against human HaCaT cells assessed as reduction in cell viability at 10 uM after 24 hrs by MTT method | Homo sapiens | 5 | ALA4196072 | cell-based format | Scientific Literature | |
4. | ALA5245179 | Binding | Agonist activity at PPAR-gamma in human BMMSC cells assessed as induction of adiponectin production at 10 uM in presence of IDX adipogenic induction medium and measured on day 5 by ELISA | Homo sapiens | 14 | ALA5244228 | cell-based format | Scientific Literature | |
5. | ALA5245180 | Binding | Displacement of Fluormone Pan-PPAR Green from GST-tagged human PPAR-gamma ligand binding domain at 10 uM by LanthaScreen TR-FRET competitive binding assay | Homo sapiens | 12 | ALA5244228 | single protein format | Scientific Literature | |
6. | ALA5245187 | Binding | Displacement of Fluormone Pan-PPAR Green from GST-tagged human PPAR-alpha ligand binding domain at 10 uM by LanthaScreen TR-FRET competitive binding assay | Homo sapiens | 12 | ALA5244228 | single protein format | Scientific Literature | |
7. | ALA5245188 | Binding | Displacement of Fluormone Pan-PPAR Green from GST-tagged human PPAR-delta ligand binding domain at 10 uM by LanthaScreen TR-FRET competitive binding assay | Homo sapiens | 12 | ALA5244228 | single protein format | Scientific Literature |