| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4189875 | B | Inhibition of Mycobacterium tuberculosis IMPDH2deltaCBS mutant expressed in Escherichia coli BL21(DE3) cells using IMP as substrate by spectrophotometric method | Mycobacterium tuberculosis | 49 | cell-based format | Scientific Literature | ||
| 2. | ALA4189876 | B | Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric method | Homo sapiens | 49 | single protein format | Scientific Literature | ||
| 3. | ALA4189877 | B | Inhibition of human GMPR2 using GMP as substrate by spectrophotometric method | Homo sapiens | 49 | single protein format | Scientific Literature | ||
| 4. | ALA4189878 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 using GAST/Fe medium after 1 week in absence of guanine by broth microdilution method | Mycobacterium tuberculosis | 32 | organism-based format | Scientific Literature | ||
| 5. | ALA4189879 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 using GAST/Fe medium after 1 week in presence of guanine by broth microdilution method | Mycobacterium tuberculosis | 32 | organism-based format | Scientific Literature | ||
| 6. | ALA4189880 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 using 7H9/ADC/Tween medium after 1 week in absence of guanine by broth microdilution method | Mycobacterium tuberculosis | 32 | organism-based format | Scientific Literature | ||
| 7. | ALA4189881 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 using 7H9/ADC/Tween medium after 1 week in presence of guanine by broth microdilution method | Mycobacterium tuberculosis | 32 | organism-based format | Scientific Literature | ||
| 8. | ALA4189882 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 using GAST/Fe medium after 2 weeks in absence of guanine by broth microdilution method | Mycobacterium tuberculosis | 8 | organism-based format | Scientific Literature | ||
| 9. | ALA4189883 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 using 7H9/ADC/Tween medium after 2 weeks in absence of guanine by broth microdilution method | Mycobacterium tuberculosis | 6 | organism-based format | Scientific Literature | ||
| 10. | ALA4189890 | A | Cytotoxicity against human HepG2 cells assessed as LDH release at 25 uM after 24 hrs relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA4189891 | A | Cytotoxicity against human HepG2 cells after 24 hrs by LDH release assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 12. | ALA4189895 | T | Selectivity index, ratio of LD50 for human HepG2 cells to MIC for Mycobacterium tuberculosis H37Rv ATCC 27294 | 5 | assay format | Scientific Literature |
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