# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4195968 | Functional | Agonist activity at SSTR1 (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-induced CRE promoter activity at 10 to 1000 nM by luciferase reporter gene assay | Homo sapiens | 3 | ALA4190409 | cell-based format | Scientific Literature | |
2. | ALA4195969 | Functional | Agonist activity at SSTR2 (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-induced CRE promoter activity at 10 to 1000 nM by luciferase reporter gene assay | Homo sapiens | 4 | ALA4190409 | cell-based format | Scientific Literature | |
3. | ALA4195970 | Functional | Agonist activity at SSTR3 (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-induced CRE promoter activity at 10 to 1000 nM by luciferase reporter gene assay | Homo sapiens | 4 | ALA4190409 | cell-based format | Scientific Literature | |
4. | ALA4195971 | Functional | Agonist activity at SSTR4 (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-induced CRE promoter activity at 10 to 1000 nM by luciferase reporter gene assay | Homo sapiens | 3 | ALA4190409 | cell-based format | Scientific Literature | |
5. | ALA4195972 | Functional | Agonist activity at SSTR5 (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-induced CRE promoter activity at 10 to 1000 nM by luciferase reporter gene assay | Homo sapiens | 4 | ALA4190409 | cell-based format | Scientific Literature | |
6. | ALA4195980 | ADME | Drug uptake in human PANC1 cells assessed as SSTR2/SSTR5-mediated drug accumulation measured after 5 to 19 hrs by DAPI staining based confocal microscopic analysis | Homo sapiens | 1 | ALA4190409 | cell-based format | Scientific Literature | |
7. | ALA4195982 | ADME | Drug uptake in human Capan1 cells assessed as SSTR2/SSTR5-mediated drug accumulation measured up to 24 hrs by DAPI staining based confocal microscopic analysis | Homo sapiens | 2 | ALA4190409 | cell-based format | Scientific Literature | |
8. | ALA4195988 | ADME | Drug uptake in tumor of athymic nude mouse xenografted with human PANC1 cells at 120 mg/kg, iv measured after 24 hrs by fluorescent microscopic analysis | Mus musculus | 2 | ALA4190409 | organism-based format | Scientific Literature | |
9. | ALA4195989 | ADME | Drug uptake in kidney of athymic nude mouse xenografted with human PANC1 cells at 120 mg/kg, iv measured after 24 hrs by fluorescent microscopic analysis | Mus musculus | 2 | ALA4190409 | organism-based format | Scientific Literature | |
10. | ALA4195990 | ADME | Drug uptake in pancreas of athymic nude mouse xenografted with human PANC1 cells at 120 mg/kg, iv measured after 24 hrs by fluorescent microscopic analysis | Mus musculus | 2 | ALA4190409 | organism-based format | Scientific Literature |