# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4193095 | Binding | Inhibition of recombinant human MMP3 (Tyr18 to Cys477 residues) expressed in mouse myeloma cells using Mca-Pro-LeuGly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Homo sapiens | 32 | ALA4190296 | cell-based format | Scientific Literature | |
2. | ALA4193096 | Binding | Inhibition of recombinant human MMP8 (Phe21 to Gly467 residues) expressed in mouse myeloma cells using Mca-Pro-LeuGly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Homo sapiens | 32 | ALA4190296 | cell-based format | Scientific Literature | |
3. | ALA4193097 | Binding | Inhibition of recombinant human MMP9 (Ala20 to Asp707 residues) expressed in CHO cells using Mca-Pro-LeuGly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Homo sapiens | 32 | ALA4190296 | cell-based format | Scientific Literature | |
4. | ALA4193098 | Functional | Antiproliferative activity against human NCI-H460 cells after 48 hrs by MTT assay | Homo sapiens | 33 | ALA4190296 | cell-based format | Scientific Literature | |
5. | ALA4193099 | Functional | Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay | Homo sapiens | 33 | ALA4190296 | cell-based format | Scientific Literature | |
6. | ALA4193100 | Functional | Antiproliferative activity against human SKOV3 cells after 48 hrs by MTT assay | Homo sapiens | 33 | ALA4190296 | cell-based format | Scientific Literature | |
7. | ALA4193101 | Functional | Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay | Homo sapiens | 33 | ALA4190296 | cell-based format | Scientific Literature | |
8. | ALA4193102 | ADME | Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay | Homo sapiens | 33 | ALA4190296 | cell-based format | Scientific Literature |