| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4193838 | B | Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrate addition measured after 20 mins in presence of 0.2 mg/ml BSA by LANCE TR-FRET assay | Homo sapiens | 7 | ALA4190335 | single protein format | Scientific Literature | |
| 2. | ALA4193839 | F | Antiproliferative activity against human KYSE-150 cells after 168 hrs by 5-bromo-2'-deoxyuridine thymidine incorporation assay | Homo sapiens | 7 | ALA4190335 | cell-based format | Scientific Literature | |
| 3. | ALA4193840 | B | Inhibition of KDM4 in human KYSE-150 cells assessed as increase in H3K9me3 level at higher concentration after 24 hrs by UHPLC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA4190335 | cell-based format | Scientific Literature | |
| 4. | ALA4193841 | B | Inhibition of KDM4 in human KYSE-150 cells assessed as increase in H3K36me3 level at higher concentration after 24 hrs by UHPLC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA4190335 | cell-based format | Scientific Literature | |
| 5. | ALA4193842 | B | Inhibition of KDM1 in human KYSE-150 cells assessed as increase in H3K4me2 level at higher concentration after 24 hrs by UHPLC-MS/MS analysis | Homo sapiens | 1 | ALA4190335 | cell-based format | Scientific Literature | |
| 6. | ALA4193843 | B | Inhibition of KDM5 in human KYSE-150 cells assessed as increase in H3K4me3 level at higher concentration after 24 hrs by UHPLC-MS/MS analysis | Homo sapiens | 1 | ALA4190335 | cell-based format | Scientific Literature | |
| 7. | ALA4193844 | B | Inhibition of KDM6 in human KYSE-150 cells assessed as increase in H3K27me3 level at higher concentration after 24 to 96 hrs by UHPLC-MS/MS analysis | Homo sapiens | 1 | ALA4190335 | cell-based format | Scientific Literature | |
| 8. | ALA4193845 | B | Inhibition of full-length KDM4C (unknown origin) expressed in human KYSE-150 cells assessed as increase in H3K36me3 level after 24 hrs by Western blot analysis | Homo sapiens | 5 | ALA4190335 | cell-based format | Scientific Literature | |
| 9. | ALA4193846 | A | Cytotoxicity against human IMR90 cells | Homo sapiens | 4 | ALA4190335 | cell-based format | Scientific Literature | |
| 10. | ALA4193849 | A | Permeability of the compound by PAMPA | 4 | ALA4190335 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!