# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4188443 | Functional | Vasodilatory activity in New Zealand White rabbit thoracic aorta assessed as relaxation of (-)-noradrenaline-induced contractile response at 0.1 uM relative to untreated control | Oryctolagus cuniculus | 17 | ALA4184267 | tissue-based format | Scientific Literature | |
2. | ALA4188444 | Functional | Vasodilatory activity in New Zealand White rabbit thoracic aorta assessed as relaxation of (-)-noradrenaline-induced contractile response at 1 uM relative to untreated control | Oryctolagus cuniculus | 17 | ALA4184267 | tissue-based format | Scientific Literature | |
3. | ALA4188445 | Functional | Vasodilatory activity in New Zealand White rabbit thoracic aorta assessed as relaxation of (-)-noradrenaline-induced contractile response at 10 uM relative to untreated control | Oryctolagus cuniculus | 17 | ALA4184267 | tissue-based format | Scientific Literature | |
4. | ALA4188446 | Functional | Antagonist activity at alpha1A-adrenoreceptor in Sprague-Dawley rat vas deferens assessed as relaxation of (-)-noradrenaline-induced contractile response | Rattus norvegicus | 7 | ALA4184267 | assay format | Scientific Literature | |
5. | ALA4188447 | Functional | Antagonist activity at alpha1B-adrenoreceptor in Sprague-Dawley rat spleen assessed as relaxation of (-)-noradrenaline-induced contractile response | Rattus norvegicus | 7 | ALA4184267 | assay format | Scientific Literature | |
6. | ALA4188448 | Functional | Antagonist activity at alpha1D-adrenoreceptor in Sprague-Dawley rat thoracic aorta assessed as relaxation of (-)-noradrenaline-induced contractile response | Rattus norvegicus | 7 | ALA4184267 | assay format | Scientific Literature | |
7. | ALA4188449 | Binding | Selectivity index, ratio of pA2 for antagonist activity at alpha1D-adrenoreceptor in Sprague-Dawley rat thoracic aorta to pA2 for antagonist activity at alpha1A-adrenoreceptor in Sprague-Dawley rat vas deferens | Rattus norvegicus | 7 | ALA4184267 | assay format | Scientific Literature | |
8. | ALA4188450 | Binding | Selectivity index, ratio of pA2 for antagonist activity at alpha1D-adrenoreceptor in Sprague-Dawley rat thoracic aorta to pA2 for antagonist activity at alpha1B-adrenoreceptor in Sprague-Dawley rat spleen | Rattus norvegicus | 7 | ALA4184267 | assay format | Scientific Literature | |
9. | ALA4188451 | Binding | Selectivity index, ratio of pA2 for alpha1A-adrenoreceptor in Sprague-Dawley rat vas deferens to pA2 for antagonist activity at alpha1B-adrenoreceptor in Sprague-Dawley rat spleen | Rattus norvegicus | 7 | ALA4184267 | assay format | Scientific Literature |